Evidence map›Paper›PMID 30024767›Full record

ArticleNano letters2018

Optics-Free, Non-Contact Measurements of Fluids, Bubbles, and Particles in Microchannels Using Metallic Nano-Islands on Graphene.

Charles Dhong, Samuel J Edmunds, Julian Ramírez, Laure V Kayser, Fang Chen, Jesse V Jokerst, Darren J Lipomi

Abstract read
In one paragraph

Article in Nano letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Lab on a chip · 2023
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Theory of the flow-induced deformation of shallow compliant microchannels with thick walls.Proceedings. Mathematical, physical, and engineering sciences · 2019
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Charles DhongDepartment of NanoEngineering , University of California, San Diego , 9500 Gilman Drive, Mail Code 0448 , La Jolla , California 92093 , United States.
Samuel J EdmundsDepartment of NanoEngineering , University of California, San Diego , 9500 Gilman Drive, Mail Code 0448 , La Jolla , California 92093 , United States.
Julian RamírezDepartment of NanoEngineering , University of California, San Diego , 9500 Gilman Drive, Mail Code 0448 , La Jolla , California 92093 , United States.
Laure V KayserDepartment of NanoEngineering , University of California, San Diego , 9500 Gilman Drive, Mail Code 0448 , La Jolla , California 92093 , United States.
Fang ChenDepartment of NanoEngineering , University of California, San Diego , 9500 Gilman Drive, Mail Code 0448 , La Jolla , California 92093 , United States.ORCID 0000-0002-6675-5508
Jesse V JokerstDepartment of NanoEngineering , University of California, San Diego , 9500 Gilman Drive, Mail Code 0448 , La Jolla , California 92093 , United States.
Darren J LipomiDepartment of NanoEngineering , University of California, San Diego , 9500 Gilman Drive, Mail Code 0448 , La Jolla , California 92093 , United States.ORCID 0000-0002-5808-7765

Funding

Stretchable, Biodegradable, and Self-Healing Semiconductors for Wearable and Implantable SensorsDP2EB022358 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LIPOMI, DARREN J · 2015 to 2020
$2.7M
Therapeutic Drug Monitoring with a Wearable Ultrasound-based SensorDP2HL137187 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2016 to 2019
$2.7M
A Therapeutic Tool for Ultrasound-Guided Stem Cell TherapyR00HL117048 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2015 to 2017
$747k
NHLBI NIH HHS DP2 HL137187NHLBI NIH HHS R00 HL117048NIBIB NIH HHS DP2 EB022358
6 · The paper itself

Abstract

Despite the apparent convenience of microfluidic technologies for applications in healthcare, such devices often rely on capital-intensive optics and other peripheral equipment that limit throughput. Here, we monitored the transit of fluids, gases, particles, and cells as they flowed through a microfluidic channel without the use of a camera or laser, i.e., "optics-free" microfluidics. We did this by monitoring the deformation of the side walls caused by the analyte passing through the channel. Critically, the analyte did not have to make contact with the channel walls to induce a deflection. This minute deformation was transduced into a change in electrical resistance using an ultrasensitive piezoresitive film composed of metallic nano-islands on graphene. We related changes in the resistance of the sensor to the theoretical deformation of the channel at varying flow rates. Then, we used air bubbles to induce a perturbation on the elastomeric channel walls and measured the viscoelastic relaxation of the walls of the channel. We obtained a viscoelastic time constant of 11.3 ± 3.5 s

Indexed as

DimethylpolysiloxanesEquipment DesignGraphiteKineticsMetal NanoparticlesMicrofluidic Analytical TechniquesNanocompositesParticle SizeSurface PropertiesViscositybaysilonDimethylpolysiloxanesGraphitebubbleselastohydrodynamicsgrapheneparticlesStrain sensorviscous fluids

Identifiers

PMID30024767
PMCPMC6174088

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.