ArticleMedicine2018
Hospitalization costs and length of stay of Japanese children with respiratory syncytial virus: A structural equation modeling approach.
Article in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 37 citations in OpenAlex.
- A phase I study to evaluate safety, pharmacokinetics, and pharmacodynamics of respiratory syncytial virus neutralizing monoclonal antibody MK-1654 in healthy Japanese adults.Clinical and translational science · 2022Trial
- Epidemiology and economic burden of hospitalizations attributable to Respiratory Syncytial Virus (RSV) infection among infants in France, 2016 to 2023 - EPIBREATHE study.BMC infectious diseases · 2025Article
- Caregiver Burden Associated With Respiratory Syncytial Virus (RSV) Infection in Young Children in Japan.Cureus · 2025Article
- Respiratory syncytial virus hospitalization costs, rates, and seasonality in Asia: a systematic review and meta-analysis.EClinicalMedicine · 2025Review
- Cost-Effectiveness and Public Health Impact of Universal Prophylaxis with Nirsevimab Against Respiratory Syncytial Virus (RSV) Infections in all Infants in Japan.Infectious diseases and therapy · 2025Article
- Factors contributing to hospitalization expenditures for patients with COPD in Yunnan Province, China: a path analysis.BMC health services research · 2024Article
- The Burden of Seasonal Influenza and Its Potential Complications Among Older Japanese Adults: A Real-World Database Study.Influenza and other respiratory viruses · 2024Article
- Cost and health-related quality of life for children hospitalized with respiratory syncytial virus in Central China.Influenza and other respiratory viruses · 2023Article
- Impact of RSV test positivity, patient characteristics, and treatment characteristics on the cost of hospitalization for acute bronchiolitis in a French university medical center (2010-2015).Frontiers in pediatrics · 2023Article
- Article
- The Long-Term Healthcare Utilization and Economic Burden of RSV Infection in Children ≤5 Years in Japan: Propensity Score Matched Cohort Study.ClinicoEconomics and outcomes research : CEOR · 2022Article
- Article
- Cost drivers associated with diffuse large B-cell lymphoma (DLBCL) in Japan: A structural equation model (SEM) analysis.PloS one · 2022Article
- Quantifying the causal impact of funding bedside antigen testing on the incidence of respiratory syncytial virus infection in Japan: a difference-in-differences study.Annals of translational medicine · 2020Article
- Burden and Cost of Hospitalization for Respiratory Syncytial Virus in Young Children, Singapore.Emerging infectious diseases · 2020Article
- Co-insurance and health care utilization in Japanese patients with rheumatoid arthritis: a discontinuity regression approach.International journal for equity in health · 2019Article
- Persistence with Biological Disease-modifying Antirheumatic Drugs and Its Associated Resource Utilization and Costs.Drugs - real world outcomes · 2018Article
- Incidence trends and disease burden of respiratory syncytial virus (RSV) infection from 2014 to 2019 before the COVID-19 pandemic in Fukushima, Japan.Pediatrics international : official journal of the Japan Pediatric SocietyArticle
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study sought to identify factors that impact the total health care costs associated with hospitalization of young Japanese children with respiratory syncytial virus (RSV).
methodsChildren admitted between April 2014 and March 2015 with at least a confirmed diagnosis of RSV and 2 days of hospital stay were considered for inclusion. Data analyses of hospital claims were performed using a structural equation modeling approach.
resultsA total of 6811 Japanese inpatients (<5 years old) diagnosed with RSV were included. The average length of stay was 7.5 days with a mean total health care cost of US Dollars (USD) $3344 per hospitalization. Intensive care unit hospitalizations were associated with greater costs (USD +$4951) compared to routine hospitalizations. The highest procedure-related cost drivers were blood transfusions (USD +$6402) and tube feedings (USD +$3512).
conclusionThe economic burden of RSV-related infection hospitalizations in Japan is considerable. Efforts should be toward immunization and therapeutic treatment strategies that reduce severity, prevent, or reduce the duration of hospitalization.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.