Evidence map›Paper›PMID 30024502›Full record

ArticleMedicine2018

Intracranial tuberculous mass lesions treated with thalidomide in an immunocompetent child from a low tuberculosis endemic country: A case report.

Emanuela Caraffa, Gianluca Russo, Serena Vita, Miriam Lichtner, Anna Paola Massetti, Claudio Maria Mastroianni, Vincenzo Vullo, Maria Rosa Ciardi, Camilla Ajassa

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Challenges in conducting trials for pediatric tuberculous meningitis: lessons from the field.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2019
    Trial
  2. Review
  3. A teenage girl with altered mental status and paraparesis.Journal of clinical tuberculosis and other mycobacterial diseases · 2024
    Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Emanuela CaraffaDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome Infectious Diseases Unit, Sapienza University, SM Goretti Hospital, Latina, Italy.
Gianluca Russo
Serena Vita
Miriam Lichtner
Anna Paola Massetti
Claudio Maria Mastroianni
Vincenzo Vullo
Maria Rosa Ciardi
Camilla Ajassa
Sapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleTuberculous meningitis is a highly morbid, often fatal disease. PATIENT CONCERN: We describe a case of an Italian child. DIAGNOSES:: we diagnosed early a Tuberculous meningitis complicated by the occurrence of hydrocephalus, stroke, and paradoxical reaction with brain pseudo-abscesses.

interventionsThe child started readily a specific therapy associated with steroids and thalidomide was introduced few month later. OUTCOMES: the patient had a favorable outcome without neurologic sequelae. LESSONS: Despite the prompt specific anti-tubercular and adjuvant corticosteroid therapies, only the addition of thalidomide to the treatment allow to a favorable clinical outcome.

Indexed as

Antitubercular AgentsBrainCerebrospinal FluidChildFemaleGlucocorticoidsHumansHydrocephalusImmunocompetenceImmunosuppressive AgentsItalyMagnetic Resonance ImagingMycobacterium tuberculosisStrokeThalidomideTreatment OutcomeAntitubercular AgentsGlucocorticoidsImmunosuppressive AgentsThalidomide

Identifiers

PMID30024502
PMCPMC6086519
OpenAlexW2884027999

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.