Evidence map›Paper›PMID 30024438›Full record

ArticleCancer nursing

Trajectories of Fasting Blood Glucose in Autologous Hematopoietic Cell Transplantation.

Marilyn J Hammer, Steven M Paul, Amir Steinberg, Patricia Eckardt, Margaret Barton-Burke, Christine Miaskowski

Abstract read
In one paragraph

Article in Cancer nursing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Hyperglycemia, symptoms, and symptom clusters in colorectal cancer survivors with type 2 diabetes.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marilyn J HammerAuthor Affiliations: Department of Nursing, Mount Sinai Hospital, New York (Dr Hammer); Department of Physiological Nursing, School of Nursing, University of California San Francisco (Drs Paul and Miaskowski); and Icahn School of Medicine, Mount Sinai Hospital (Dr Steinberg); Heilbrunn Family Center for Research Nursing, Rockefeller University (Dr Eckardt); and Department of Nursing, Memorial Sloan Kettering Cancer Center (Dr Barton-Burke), New York.
Steven M Paul
Amir Steinberg
Patricia Eckardt
Margaret Barton-Burke
Christine Miaskowski

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Glycemic Status and Infections in Autologous HCT RecipientsK23NR012467 · NINR · NEW YORK UNIVERSITY · PI HAMMER, MARILYN J · 2010 to 2012
$316k
NCI NIH HHS P30 CA008748NINR NIH HHS K23 NR012467
6 · The paper itself

Abstract

backgroundPatients who receive autologous hematopoietic cell transplantation (HCT) for the treatment of hematologic malignancies are at risk of serious adverse outcomes including infections and death. Hyperglycemia following the HCT is associated with increased risk of these adverse outcomes. However, limited information is available on demographic and clinical characteristics that contribute to changes in blood glucose levels following HCT.

objectiveThe objective of this study was to determine the trajectories of fasting blood glucose (FBG) levels as well as the demographic and clinical characteristics that predicted interindividual differences in these FBG trajectories.

methodsA sample of adult patients with hematologic malignancies who were scheduled to receive autologous HCT (n = 53) was enrolled in the study. Patients with preexisting diabetes were excluded. Demographic and clinical characteristics were abstracted from electronic medical records. Morning fasting laboratory tests (ie, FBG and absolute neutrophil counts) were obtained. Data were analyzed using hierarchical linear modeling from the day of HCT (day 0) through 14 days post-HCT.

resultsAmong 8 characteristics evaluated, pre-HCT FBG was associated with variability in both the initial levels and the trajectories of FBG. Body mass index was only associated with initial levels of FBG.

conclusionsThe large amount of interindividual variability in the trajectories of FBG levels following autologous HCT suggests that glucose control in these patients warrants ongoing assessments and preemptive tailoring. IMPLICATIONS FOR PRACTICE: Fasting blood glucose monitoring is warranted. Additional research with larger samples is warranted to identify additional modifiable and nonmodifiable characteristics associated with interindividual variability in FBG levels.

Indexed as

AdultBlood GlucoseBlood Glucose Self-MonitoringFastingFemaleHematologic NeoplasmsHematopoietic Stem Cell TransplantationHumansHyperglycemiaMaleMiddle AgedBlood Glucose

Identifiers

PMID30024438
PMCPMC6336533

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.