Evidence map›Paper›PMID 30024366›Full record

ArticleMicrobial genomics2018

Trends in fluoroquinolone resistance in Campylobacter.

Emma L Sproston, Helen M L Wimalarathna, Samuel K Sheppard

Open access · goldAbstract read
In one paragraph

Article in Microbial genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed, 4 pooled it
15.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 4 syntheses or guidelines pooled it, 159 citations in OpenAlex.

  1. Pooled it
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  14. Antimicrobial Susceptibility ofVeterinary sciences · 2025
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40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Emma L Sproston1​The Milner Centre for Evolution, Department of Biology and Biochemistry, University of Bath, Bath BA27AY, UK.
Helen M L Wimalarathna2​School of Medicine University of Central Lancashire, Preston, Lancashire PR1 2HE, UK.
Samuel K Sheppard1​The Milner Centre for Evolution, Department of Biology and Biochemistry, University of Bath, Bath BA27AY, UK.
University of Bath · GBUniversity of Central Lancashire · GB

Funding

Biotechnology and Biological Sciences Research Council BB/I02464X/1Medical Research Council G0801929Medical Research Council MR/L015080/1Wellcome Trust
6 · The paper itself

Abstract

Members of the genus Campylobacter remain a leading cause of bacterial gastroenteritis worldwide. Infection is usually self-limiting but in severe cases may require antibiotic treatment. In a recent statement by the World Health Organization (WHO) Campylobacter was named as one of the 12 bacteria that pose the greatest threat to human health because they are resistant to antibiotics. In this mini review we describe recent trends in fluoroquinolone (FQ) (particularly ciprofloxacin) resistance in strains of members of the genus Campylobacter isolated from livestock and clinical samples from several countries. Using evidence from phenotyping surveys and putative resistance prediction from DNA sequence data, we discuss the acquisition and spread of FQ resistance and the role of horizontal gene transfer and describe trends in FQ-resistance in samples from livestock and clinical cases. This review emphasises that FQ resistance remains common among isolates of members of the genus Campylobacter from various sources.

Indexed as

CiprofloxacinGene Transfer, HorizontalAnimalsCampylobacterDrug Resistance, BacterialHumansCiprofloxacinCampylobacterciprofloxacinfluoroquinolonesresistance

Identifiers

PMID30024366
PMCPMC6159550
OpenAlexW2883257540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.