Evidence map›Paper›PMID 30024341›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2018

Sex differences in large conducting airway anatomy.

Paolo B Dominelli, Juan G Ripoll, Troy J Cross, Sarah E Baker, Chad C Wiggins, Brian T Welch, Michael J Joyner

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06939361 (The Tube Size Randomized Trial During Emergency Tracheal Intubation), which is not on this map. Cited by 68 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 1 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06939361 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

The Tube Size Randomized Trial During Emergency Tracheal Intubation

TypeinterventionalSponsorVanderbilt University Medical CenterRan2025 to 2029Enrolled3,180ConditionsAcute Respiratory FailureArmsSmaller endotracheal tube, Larger endotracheal tube
3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 1 synthesis or guideline pooled it, 142 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Sexually distinct multi-omic responses to progressive endurance exercise training in the rat lung.American journal of respiratory cell and molecular biology · 2026
    Article
  6. The upper airway in obstructive sleep apnoea: state of the art.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Observational
  12. Article
  13. External mechanical efficiency across incremental VOCurrent research in physiology · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Observational
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Paolo B DominelliDepartment of Anesthesiology, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0001-5575-4043
Juan G RipollDepartment of Anesthesiology, Mayo Clinic, Rochester, Minnesota.
Troy J CrossDepartment of Cardiovascular Disease, Mayo Clinic, Rochester, Minnesota.
Sarah E BakerDepartment of Anesthesiology, Mayo Clinic, Rochester, Minnesota.
Chad C WigginsDepartment of Anesthesiology, Mayo Clinic, Rochester, Minnesota.
Brian T WelchDepartment of Radiology, Mayo Clinic, Rochester, Minnesota.
Michael J JoynerDepartment of Anesthesiology, Mayo Clinic, Rochester, Minnesota.
Mayo Clinic · USGriffith University · AU

Funding

DIABETES AND METABOLISMT32DK007352 · NIDDK · MAYO CLINIC ROCHESTER · PI MICHAEL D. JENSEN · 1986 to 2026
$9.4M
Variant Hemoglobin and Cardiorespiratory Regulation in HumansR35HL139854 · NHLBI · MAYO CLINIC ROCHESTER · PI JOYNER, MICHAEL J · 2018 to 2024
$5.8M
Improving Drug Delivery In Individuals With Cystic Fibrosis Using ExerciseF32HL131151 · NHLBI · MAYO CLINIC ROCHESTER · PI BAKER, SARAH ELIZABETH · 2016 to 2017
$84k
NHLBI NIH HHS F32 HL131151NHLBI NIH HHS R35 HL139854NIDDK NIH HHS T32 DK007352
6 · The paper itself

Abstract

Airway luminal area is the major determinant of resistance to airflow in the tracheobronchial tree. Women may have smaller central conducting airways than men; however, previous evidence is confounded by an indirect assessment of airway geometry and by subjects with prior smoking history. The purpose of this study was to examine the effect of sex on airway size in healthy nonsmokers. Using low-dose high-resolution computed tomography, we retrospectively assessed airway luminal area in healthy men ( n = 51) and women ( n = 73) of varying ages (19-86 yr). Subjects with a positive smoking history, cardiopulmonary disease, or a body mass index > 40 kg/m

Indexed as

AdultAgedAged, 80 and overBody HeightBronchiFemaleHealthy VolunteersHumansLungMaleMiddle AgedRespiratory Function TestsRespiratory SystemRetrospective StudiesSex CharacteristicsTomography, X-Ray Computeddysanapsisexercisework of breathing

Identifiers

PMID30024341
PMCPMC6335094
OpenAlexW2883816582

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.