Evidence map›Paper›PMID 30023881›Full record

ArticleACS omega2018

Colorimetric Immunosensor by Aggregation of Photochemically Functionalized Gold Nanoparticles.

Marzia Iarossi, Chiara Schiattarella, Ilaria Rea, Luca De Stefano, Rosalba Fittipaldi, Antonio Vecchione, Raffaele Velotta, Bartolomeo Della Ventura

Abstract read
In one paragraph

Article in ACS omega, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Nanotheranostics: application of nanosensors in diabetes management.Journal of diabetes and metabolic disorders · 2023
    Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. A model of modifiedRSC advances · 2021
    Article
  13. Review
  14. Immunodiagnostic of Vibrio cholerae O1 using localized surface plasmon resonance (LSPR) biosensor.International microbiology : the official journal of the Spanish Society for Microbiology · 2021
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marzia IarossiDepartment of Physics "E. Pancini", Università di Napoli "Federico II", Via Cintia, 26 Ed. 6, 80126 Napoli, Italy.
Chiara SchiattarellaDepartment of Physics "E. Pancini", Università di Napoli "Federico II", Via Cintia, 26 Ed. 6, 80126 Napoli, Italy.
Ilaria ReaNational Research Council, Institute for Microelectronics and Microsystems, Unit of Naples, Via P. Castellino 111, 80131 Napoli, Italy.
Luca De StefanoNational Research Council, Institute for Microelectronics and Microsystems, Unit of Naples, Via P. Castellino 111, 80131 Napoli, Italy.
Rosalba FittipaldiNational Research Council, SPIN Institute, Unit of Salerno and Department of Physics "E. R. Caianiello", Università di Salerno, Via Ponte don Mellillo, 84084 Fisciano, Salerno, Italy.
Antonio VecchioneNational Research Council, SPIN Institute, Unit of Salerno and Department of Physics "E. R. Caianiello", Università di Salerno, Via Ponte don Mellillo, 84084 Fisciano, Salerno, Italy.
Raffaele VelottaDepartment of Physics "E. Pancini", Università di Napoli "Federico II", Via Cintia, 26 Ed. 6, 80126 Napoli, Italy.
Bartolomeo Della VenturaDepartment of Physics "E. Pancini", Università di Napoli "Federico II", Via Cintia, 26 Ed. 6, 80126 Napoli, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A colorimetric immunosensor based on local surface plasmon resonance by gold nanoparticles is presented, and its application for the detection of human immunoglobulin G (IgG) is demonstrated. The color change of the colloidal solution is produced by nanoparticle aggregation, a process that can be tuned by the presence of the analyte once the nanoparticles are functionalized. In comparison to common functionalization techniques, the procedure described here is simpler, low-cost, and effective in binding antibodies upright on the gold surface. The dose-response curve is similar to that resulting in typical immunoassay platforms and is satisfactorily described by the proposed theoretical model. Human IgG at concentration levels of few hundreds of nanograms per milliliter can be detected by eyes within a few minutes, thereby making the colorimetric immunosensor proposed here a powerful tool in several areas, with urine test in medical diagnostics being the most immediate.

Identifiers

PMID30023881
PMCPMC6044629

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.