Evidence map›Paper›PMID 30023863›Full record

ArticleACS omega2018

Structural Switch from Hairpin to Duplex/Antiparallel G-Quadruplex at Single-Nucleotide Polymorphism (SNP) Site of Human Apolipoprotein E (

Swati Chaudhary, Mahima Kaushik, Saami Ahmed, Ritushree Kukreti, Shrikant Kukreti

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Review
  5. Article
  6. G-quadruplex structural variations in human genome associated with single-nucleotide variations and their impact on gene activity.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  7. Modulation of DNA structure formation using small molecules.Biochimica et biophysica acta. Molecular cell research · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Swati ChaudharyNucleic Acids Research Lab, Department of Chemistry and Cluster Innovation Center, University of Delhi, Delhi 110007, India.
Mahima KaushikNucleic Acids Research Lab, Department of Chemistry and Cluster Innovation Center, University of Delhi, Delhi 110007, India.
Saami AhmedNucleic Acids Research Lab, Department of Chemistry and Cluster Innovation Center, University of Delhi, Delhi 110007, India.
Ritushree KukretiCSIR-Institute of genomics and Integrative Biology, Delhi 110007, India.
Shrikant KukretiNucleic Acids Research Lab, Department of Chemistry and Cluster Innovation Center, University of Delhi, Delhi 110007, India.
University of Delhi · INInstitute of Genomics and Integrative Biology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A gradual dementia, which leads to the loss of memory and intellectual abilities, is the main characteristics of Alzheimer's disease. Amyloid-β (Aβ) plaques are the main components that accumulate and form clumps in the brains of people suffering from Alzheimer's disease. Apolipoprotein E (

Identifiers

PMID30023863
PMCPMC6045395
OpenAlexW2794289687

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.