Evidence map›Paper›PMID 30023824›Full record

ArticleACS omega2018

Single Platform for Gene and Protein Expression Analyses Using Luminescent Gold Nanoclusters.

Sunil Kumar Sailapu, Deepanjalee Dutta, Amaresh Kumar Sahoo, Siddhartha Sankar Ghosh, Arun Chattopadhyay

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sunil Kumar SailapuCentre for Nanotechnology, Department of Biosciences and Bioengineering, and Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781 039, Assam, India.
Deepanjalee DuttaCentre for Nanotechnology, Department of Biosciences and Bioengineering, and Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781 039, Assam, India.
Amaresh Kumar SahooCentre for Nanotechnology, Department of Biosciences and Bioengineering, and Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781 039, Assam, India.
Siddhartha Sankar GhoshCentre for Nanotechnology, Department of Biosciences and Bioengineering, and Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781 039, Assam, India.
Arun ChattopadhyayCentre for Nanotechnology, Department of Biosciences and Bioengineering, and Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781 039, Assam, India.
Indian Institute of Technology Guwahati · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A single platform for gene and protein expression studies is proposed to pursue rapid diagnostics. A common method to synthesize gold (Au) nanoclusters on both DNA and protein template was developed using a benchtop device. The method of synthesis is rapid and versatile and can be applied to different classes of DNA/protein. Employing luminescent Au nanoclusters as the signal-generating agents, the device enables carrying out reverse transcriptase polymerase chain reaction and array-based analyses of multiple genes/proteins simultaneously using switchable holders and custom-designed software. The device and methods were applied to evaluate gene profiling related to apoptosis in HeLa cancer cells and further to analyze the protein expressions of glutathione-

Identifiers

PMID30023824
PMCPMC6045389
OpenAlexW2788111741

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.