Evidence map›Paper›PMID 30023770›Full record

ArticleACS omega2018

Metallofluorescent Nanoparticles for Multimodal Applications.

Antonio Delgado-Gonzalez, Emilio Garcia-Fernandez, Teresa Valero, M Victoria Cano-Cortes, Maria J Ruedas-Rama, Asier Unciti-Broceta, Rosario M Sanchez-Martin, Juan J Diaz-Mochon, Angel Orte

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Antonio Delgado-GonzalezDepartment of Medicinal and Organic Chemistry, Faculty of Pharmacy, and Department of Physical Chemistry, Faculty of Pharmacy, University of Granada, Campus Cartuja, 18071 Granada, Spain.
Emilio Garcia-FernandezDepartment of Medicinal and Organic Chemistry, Faculty of Pharmacy, and Department of Physical Chemistry, Faculty of Pharmacy, University of Granada, Campus Cartuja, 18071 Granada, Spain.
Teresa ValeroDepartment of Medicinal and Organic Chemistry, Faculty of Pharmacy, and Department of Physical Chemistry, Faculty of Pharmacy, University of Granada, Campus Cartuja, 18071 Granada, Spain.
M Victoria Cano-CortesGENYO, Pfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research, Avda. Ilustracion 114. PTS, 18016 Granada, Spain.
Maria J Ruedas-RamaDepartment of Medicinal and Organic Chemistry, Faculty of Pharmacy, and Department of Physical Chemistry, Faculty of Pharmacy, University of Granada, Campus Cartuja, 18071 Granada, Spain.
Asier Unciti-BrocetaCancer Research UK Edinburgh Centre, Institute of Genetics and Molecular Medicine, The University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, U.K.
Rosario M Sanchez-MartinDepartment of Medicinal and Organic Chemistry, Faculty of Pharmacy, and Department of Physical Chemistry, Faculty of Pharmacy, University of Granada, Campus Cartuja, 18071 Granada, Spain.
Juan J Diaz-MochonDepartment of Medicinal and Organic Chemistry, Faculty of Pharmacy, and Department of Physical Chemistry, Faculty of Pharmacy, University of Granada, Campus Cartuja, 18071 Granada, Spain.
Angel OrteDepartment of Medicinal and Organic Chemistry, Faculty of Pharmacy, and Department of Physical Chemistry, Faculty of Pharmacy, University of Granada, Campus Cartuja, 18071 Granada, Spain.
Pfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research · ESUniversidad de Granada · ESEdinburgh Cancer Research · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we describe the synthesis and application of cross-linked polystyrene-based dual-function nano- and microparticles containing both fluorescent tags and metals. Despite containing a single dye, these particles exhibit a characteristic dual-band fluorescence emission. Moreover, these particles can be combined with different metal ions to obtain hybrid metallofluorescent particles. We demonstrate that these particles are easily nanofected into living cells, allowing them to be used for effective fingerprinting in multimodal fluorescence-based and mass spectrometry-based flow cytometry experiments. Likewise, the in situ reductions of the metal ions enable other potential uses of the particles as heterogeneous catalysts.

Identifiers

PMID30023770
PMCPMC6044963
OpenAlexW2782537959

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.