ArticleACS omega2017
Preparation of a Peptide-Modified Electrode for Capture and Voltammetric Determination of Endotoxin.
Article in ACS omega, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- High-sensitivity electrochemical aptasensor based on AuNPs/NHMikrochimica acta · 2026Article
- Electrochemical plasmonic sensing strategy for sensitive detection of gram-negative endotoxin in blood samples.Biomedical optics express · 2025Article
- Highly Sensitive Electrochemical Endotoxin Sensor Based on Redox Cycling Using an Interdigitated Array Electrode Device.Micromachines · 2023Article
- Article
- Recent Advances in Electrochemical Sensors and Biosensors for Detecting Bisphenol A.Sensors (Basel, Switzerland) · 2020Review
- Photocatalytically renewable peptide-based electrochemical impedance method for sensing lipopolysaccharide.Mikrochimica acta · 2020Article
- An aptamer-based shear horizontal surface acoustic wave biosensor with a CVD-grown single-layered graphene film for high-sensitivity detection of a label-free endotoxin.Microsystems & nanoengineering · 2020Article
- Highly Sensitive Endotoxin Assay Combining Peptide/Graphene Oxide and DNA-Modified Gold Nanoparticles.ACS omega · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endotoxin is the major structural constituent of the outer membrane of Gram-negative bacteria, which is a great threat to human health. Herein, a sensitive electrochemical biosensor for the detection of endotoxin is established by recording the voltammetric responses of the peptide-modified electrode. The utilized peptide has a high affinity for the target endotoxin, which ensures the high selectivity of this method. After the capture of endotoxin on the electrode surface, a negatively charged layer is formed, and the electron-transfer process is significantly hindered because of the increased steric hindrance and the electrostatic repulsion. The declined electrochemical signal could be used to indicate the concentration of endotoxin. This method is simple but effective, which requires limited reagents. Another highlight of this method is its user-friendly operation. Moreover, its applicability in human blood plasma promises its great potential utility in the near future.
Identifiers
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Registered trials
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