Evidence map›Paper›PMID 30023546›Full record

ArticleACS omega2017

Surface Modification of Silicon Pillar Arrays To Enhance Fluorescence Detection of Uranium and DNA.

Danielle R Lincoln, Jennifer J Charlton, Nahla A Hatab, Brittany Skyberg, Nickolay V Lavrik, Ivan I Kravchenko, James A Bradshaw, Michael J Sepaniak

Abstract read
In one paragraph

Article in ACS omega, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Danielle R LincolnDepartment of Chemistry, The University of Tennessee Knoxville, 552 Buehler Hall, 1420 Circle Dr., Knoxville, Tennessee 37996, United States.
Jennifer J CharltonDepartment of Chemistry, The University of Tennessee Knoxville, 552 Buehler Hall, 1420 Circle Dr., Knoxville, Tennessee 37996, United States.
Nahla A HatabDepartment of Chemistry, The University of Tennessee Knoxville, 552 Buehler Hall, 1420 Circle Dr., Knoxville, Tennessee 37996, United States.
Brittany SkybergDepartment of Chemistry, The University of Tennessee Knoxville, 552 Buehler Hall, 1420 Circle Dr., Knoxville, Tennessee 37996, United States.
Nickolay V LavrikThe Center for Nanophase Material Sciences, Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, Tennessee 37830, United States.
Ivan I KravchenkoThe Center for Nanophase Material Sciences, Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, Tennessee 37830, United States.
James A BradshawY-12 National Security Complex, Oak Ridge Metrology Organization, P.O. Box 2009, Oak Ridge, Tennessee 37830, United States.
Michael J SepaniakDepartment of Chemistry, The University of Tennessee Knoxville, 552 Buehler Hall, 1420 Circle Dr., Knoxville, Tennessee 37996, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is an ever-growing need for detection methods that are both sensitive and efficient, such that reagent and sample consumption is minimized. Nanopillar arrays offer an attractive option to fill this need by virtue of their small scale in conjunction with their field enhancement intensity gains. This work investigates the use of nanopillar substrates for the detection of the uranyl ion and DNA, two analytes unalike but for their low quantum efficiencies combined with the need for high-throughput analyses. Herein, the adaptability of these platforms was explored, as methods for the successful surface immobilization of both analytes were developed and compared, resulting in a limit of detection for the uranyl ion of less than 1 ppm with a 0.2 μL sample volume. Moreover, differentiation between single-stranded and double-stranded DNA was possible, including qualitative identification between double-stranded DNA and DNA of the same sequence, but with a 10-base-pair mismatch.

Identifiers

PMID30023546
PMCPMC6045356

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.