Evidence map›Paper›PMID 30023476›Full record

ArticleACS omega2016

Nanoprobes for Multimodal Visualization of Bone Mineral Phase in Magnetic Resonance and Near-Infrared Optical Imaging.

Pradeep P Wyss, Laura C Herrera, Nel S Bouteghmes, Melika Sarem, Wilfried Reichardt, Jochen Leupold, Jürgen Hennig, V Prasad Shastri

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Multifunctional Magnetic Resonance Imaging Probes.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  2. Biomaterials for Orthopaedic Diagnostics and Theranostics.Current opinion in biomedical engineering · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Pradeep P WyssInstitute for Macromolecular Chemistry, University of Freiburg, Stefan Meier Strasse 31, 79104 Freiburg, Germany.
Laura C HerreraInstitute for Macromolecular Chemistry, University of Freiburg, Stefan Meier Strasse 31, 79104 Freiburg, Germany.
Nel S BouteghmesInstitute for Macromolecular Chemistry, University of Freiburg, Stefan Meier Strasse 31, 79104 Freiburg, Germany.
Melika SaremInstitute for Macromolecular Chemistry, University of Freiburg, Stefan Meier Strasse 31, 79104 Freiburg, Germany.
Wilfried ReichardtGerman Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Jochen LeupoldRadiology-Medical Physics, University Medical Center Freiburg, Breisacher Strasse 60a, 79106 Freiburg, Germany.
Jürgen HennigRadiology-Medical Physics, University Medical Center Freiburg, Breisacher Strasse 60a, 79106 Freiburg, Germany.
V Prasad ShastriInstitute for Macromolecular Chemistry, University of Freiburg, Stefan Meier Strasse 31, 79104 Freiburg, Germany.
University of Freiburg · DEUniversity Medical Center Freiburg · DEGerman Cancer Research Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Imaging agents with affinity for bone can enable early detection of changes to bone mineral density, which is a hallmark of many bone-associated pathologies such as Paget's disease and osteoporosis. Here, we report the development of a polymer nanoparticle (NP)-based multimodal imaging probe that enables visualization of bone mineral phase in near-infrared (NIR) optical tomography and detection in

Identifiers

PMID30023476
PMCPMC6044643
OpenAlexW2514583728

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.