Evidence map›Paper›PMID 30023439›Full record

ArticleBiochemistry and biophysics reports2018

Paul D Hamilton, Usha P Andley

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Biochemistry and biophysics reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Paul D HamiltonDepartment of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.
Usha P AndleyDepartment of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.

Funding

WASHINGTON UNIVERSITY CENTER VISION RESEARCHP30EY002687 · NEI · WASHINGTON UNIVERSITY · PI Philip Raymond Williams · 1985 to 2026
$18.4M
ROLE OF OXYGEN IN OCULAR PATHOLOGYR01EY005681 · NEI · WASHINGTON UNIVERSITY · PI ANDLEY, USHA P · 1985 to 2018
$7.3M
NEI NIH HHS P30 EY002687NEI NIH HHS R01 EY005681
6 · The paper itself

Abstract

The aggregation of crystallins in lenses is associated with cataract formation. We previously reported that mutant crystallins are associated with an increased abundance of histones in knock-in and knockout mouse models. However, very little is known about the specific interactions between lens crystallins and histones. Here, we performed

Indexed as

CataractComplex formationCrystallinGPC, gel permeation chromatographyHistoneHS, high saltITC, isothermal titration calorimetryMALDI-TOF MS, matrix-assisted laser-desorption/ionization-time of flight mass spectrometryPBS, phosphate-buffered salineRALS, right-angle light scattering

Identifiers

PMID30023439
PMCPMC6047474
OpenAlexW2807696504

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.