Evidence map›Paper›PMID 30023404›Full record

ArticleOrthopaedic journal of sports medicine2018

In Vivo Assessment of Exercise-Induced Glenohumeral Cartilage Strain.

Hanci Zhang, Lauren N Heckelman, Charles E Spritzer, Kwadwo A Owusu-Akyaw, John T Martin, Dean C Taylor, C T Moorman, Grant E Garrigues, Louis E DeFrate

Abstract read
In one paragraph

Article in Orthopaedic journal of sports medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hanci ZhangDepartment of Orthopaedic Surgery, James R. Urbaniak, MD, Sports Sciences Institute, Duke University, Durham, North Carolina, USA.
Lauren N HeckelmanDepartment of Orthopaedic Surgery, James R. Urbaniak, MD, Sports Sciences Institute, Duke University, Durham, North Carolina, USA.
Charles E SpritzerDepartment of Radiology, Duke University, Durham, North Carolina, USA.
Kwadwo A Owusu-AkyawDepartment of Orthopaedic Surgery, James R. Urbaniak, MD, Sports Sciences Institute, Duke University, Durham, North Carolina, USA.
John T MartinDepartment of Orthopaedic Surgery, James R. Urbaniak, MD, Sports Sciences Institute, Duke University, Durham, North Carolina, USA.
Dean C TaylorDepartment of Orthopaedic Surgery, James R. Urbaniak, MD, Sports Sciences Institute, Duke University, Durham, North Carolina, USA.
C T MoormanDepartment of Orthopaedic Surgery, James R. Urbaniak, MD, Sports Sciences Institute, Duke University, Durham, North Carolina, USA.
Grant E GarriguesDepartment of Orthopaedic Surgery, James R. Urbaniak, MD, Sports Sciences Institute, Duke University, Durham, North Carolina, USA.
Louis E DeFrateDepartment of Orthopaedic Surgery, James R. Urbaniak, MD, Sports Sciences Institute, Duke University, Durham, North Carolina, USA.

Funding

In Vivo Knee Motion and ACL Biomechanics During Dynamic ActivitiesR01AR065527 · NIAMS · DUKE UNIVERSITY · PI DEFRATE, LOUIS E. · 2014 to 2024
$4.8M
Age-related alterations in the in vivo mechanical function of the spineF32AR071223 · NIAMS · DUKE UNIVERSITY · PI MARTIN, JOHN · 2017 to 2019
$178k
NIAMS NIH HHS F32 AR071223NIAMS NIH HHS R01 AR065527
6 · The paper itself

Abstract

backgroundThe human shoulder joint is the most mobile joint in the body. While in vivo shoulder kinematics under minimally loaded conditions have been studied, it is unclear how glenohumeral cartilage responds to high-demand loaded exercise. HYPOTHESIS: A high-demand upper extremity exercise, push-ups, will induce compressive strain in the glenohumeral articular cartilage, which can be measured with validated magnetic resonance imaging (MRI)-based techniques. STUDY

designDescriptive laboratory study.

methodsHigh-resolution MRI was used to measure in vivo glenohumeral cartilage thickness before and after exercise among 8 study participants with no history of upper extremity injury or disease. Manual MRI segmentation and 3-dimensional modeling techniques were used to generate pre- and postexercise thickness maps of the humeral head and glenoid cartilage. Strain was calculated as the difference between pre- and postexercise cartilage thickness, normalized to the pre-exercise cartilage thickness.

resultsSignificant compressive cartilage strains of 17% ± 6% and 15% ± 7% (mean ± 95% CI) were detected in the humeral head and glenoid cartilage, respectively. The anterior region of the glenoid cartilage experienced a significantly higher mean strain (19% ± 6%) than the posterior region of the glenoid cartilage (12% ± 8%). No significant regional differences in postexercise humeral head cartilage strain were observed.

conclusionPush-ups induce compressive strain on the glenohumeral joint articular cartilage, particularly at the anterior glenoid. This MRI-based methodology can be applied to further the understanding of chondral changes in the shoulder under high-demand loading conditions. CLINICAL RELEVANCE: These results improve the understanding of healthy glenohumeral cartilage mechanics in response to loaded upper extremity exercise. In the future, these methods can be applied to identify which activities induce high glenohumeral cartilage strains and deviations from normal shoulder function.

Indexed as

articular cartilagebiomechanicsmagnetic resonance imaging (MRI)shoulder

Identifiers

PMID30023404
PMCPMC6047251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.