Evidence map›Paper›PMID 30023261›Full record

ReviewJournal of microscopy and ultrastructure

Anti-Quorum Sensing Natural Compounds.

Hani Z Asfour

Open access · greenAbstract readReview
In one paragraph

Review in Journal of microscopy and ultrastructure. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 287 citations in OpenAlex.

  1. Review
  2. Research Progress on the Quorum Sensing System ofPathogens (Basel, Switzerland) · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Multimodal Inhibition ofJournal of agricultural and food chemistry · 2025
    Article
  10. Review
  11. Article
  12. Microorganisms · 2025
    Article
  13. Application of bacterioruberin fromFood chemistry. Molecular sciences · 2025
    Article
  14. Article
  15. Article
  16. Review
  17. Dinuclear Gallium(III) Complex With 1,3-Propanediamine-Bioinorganic chemistry and applications · 2025
    Article
  18. Biofilm · 2024
    Article
  19. Beyond the Nut:Foods (Basel, Switzerland) · 2024
    Review
  20. Review

51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Hani Z AsfourDepartment of Medical Microbiology and Parasitology, Faculty of Medicine, Princess Al-Jawhara Center of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia.
King Abdulaziz University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing extent of pathogenic resistance to drugs has encouraged the seeking for new anti-virulence drugs. Many pharmacological and pharmacognostical researches are performed to identify new drugs or discover new structures for the development of novel therapeutic agents in the antibiotic treatments. Although many phytochemicals show prominent antimicrobial activity, their power lies in their anti-virulence properties. Quorum sensing (QS) is a bacterial intercellular communication mechanism, which depends on bacterial cell population density and controls the pathogenesis of many organisms by regulating gene expression, including virulence determinants. QS has become an attractive target for the development of novel anti-infective agents that do not rely on the use of antibiotics. Anti-QS compounds are known to have the ability to prohibit bacterial pathogenicity. Medicinal plants offer an attractive repertoire of phytochemicals with novel microbial disease-controlling potential, due to the spectrum of secondary metabolites present in extracts, which include phenolics, quinones, flavonoids, alkaloids, terpenoids, and polyacetylenes. They have recently received considerable attention as a new source of safe and effective QS inhibitory substances. The objective of this review is to give a brief account of the research reports on the plants and natural compounds with anti-QS potential.

Indexed as

Anti-virulencebacterial pathogenicitynatural productsquorum sensing

Identifiers

PMID30023261
PMCPMC6014249
OpenAlexW2591275674

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.