Evidence map›Paper›PMID 30022979›Full record

ArticleFrontiers in immunology2018

The Transcription Factor Zfx Regulates Peripheral T Cell Self-Renewal and Proliferation.

Matthew R Smith-Raska, Teresita L Arenzana, Louise M D'Cruz, Alireza Khodadadi-Jamayran, Aristotelis Tsirigos, Ananda W Goldrath, Boris Reizis

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Histone lactylation drives CD8Nature immunology · 2024
    Article
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  3. MicroRNA-495: a therapeutic and diagnostic tumor marker.Journal of molecular histology · 2023
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Matthew R Smith-RaskaDepartment of Microbiology and Immunology, Columbia University Medical Center, New York, NY, United States.
Teresita L ArenzanaDepartment of Microbiology and Immunology, Columbia University Medical Center, New York, NY, United States.
Louise M D'CruzDivision of Biological Sciences, University of California San Diego, La Jolla, CA, United States.
Alireza Khodadadi-JamayranApplied Bioinformatics Laboratories, NYU School of Medicine, New York, NY, United States.
Aristotelis TsirigosApplied Bioinformatics Laboratories, NYU School of Medicine, New York, NY, United States.
Ananda W GoldrathDivision of Biological Sciences, University of California San Diego, La Jolla, CA, United States.
Boris ReizisDepartment of Microbiology and Immunology, Columbia University Medical Center, New York, NY, United States.
New York University · USColumbia University Irving Medical Center · USUniversity of California, San Diego · US

Funding

T cell maintenance: molecular mediators of T cell differentiation and survivalR37AI067545 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ananda W Goldrath · 2022 to 2026
$3.0M
NIAID NIH HHS R37 AI067545
6 · The paper itself

Abstract

Peripheral T lymphocytes share many functional properties with hematopoietic stem cells (HSCs), including long-term maintenance, quiescence, and latent proliferative potential. In addition, peripheral T cells retain the capacity for further differentiation into a variety of subsets, much like HSCs. While the similarities between T cells and HSC have long been hypothesized, the potential common genetic regulation of HSCs and T cells has not been widely explored. We have studied the T cell-intrinsic role of

Indexed as

hematopoietic stem cellhomeostatic proliferationT cell homeostasisT cell self-renewalT cell stress response

Identifiers

PMID30022979
PMCPMC6039547
OpenAlexW2807800143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.