Evidence map›Paper›PMID 30022819›Full record

ArticleInternational journal of nanomedicine2018

Nanostructured Ti surfaces and retinoic acid/dexamethasone present a spatial framework for the maturation and amelogenesis of LS-8 cells.

Nan Jiang, Lu Chen, Qianli Ma, Jianping Ruan

Abstract read
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In one paragraph

Article in International journal of nanomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nan JiangDepartment of Preventive Dentistry, College of Stomatology, Xi'an JiaoTong University, Xi'an, People's Republic of China, ruanjp@xjtu.edu.cn.
Lu ChenDepartment of Preventive Dentistry, College of Stomatology, Xi'an JiaoTong University, Xi'an, People's Republic of China, ruanjp@xjtu.edu.cn.
Qianli MaDepartment of Immunology, School of Basic Medicine, Fourth Military Medical University, Xi'an, People's Republic of China, mqlkyo99@hotmail.com.
Jianping RuanDepartment of Preventive Dentistry, College of Stomatology, Xi'an JiaoTong University, Xi'an, People's Republic of China, ruanjp@xjtu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the amelogenesis-inductive effects of surface structures at the nanoscale. For this purpose, variable nanostructured titanium dioxide (TiO MATERIALS AND

methodsTiO

resultsTiO

conclusionControlling the amelogenic behaviors of ameloblast-like LS-8 cells by manipulating the nanostructure of biomaterials surfaces represents an effective tool for the establishment of a systemic framework for supporting enamel regeneration. The administration of RA/DEX is an effective approach for driving the amelogenesis and maturation of ameloblasts.

Indexed as

AmeloblastsAmelogenesisAnimalsApoptosisCalcification, PhysiologicCell AdhesionCell DifferentiationCell LineCell ProliferationCells, CulturedCell ShapeDexamethasoneExtracellular MatrixGene Expression RegulationMiceNanostructuresDexamethasoneTitaniumtitanium dioxideTretinoinamelogenesisLS-8retinoic acidsurface nanostructureTiO2 nanotube

Identifiers

PMID30022819
PMCPMC6042561

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.