Evidence map›Paper›PMID 30022768›Full record

ArticlePhysics in medicine and biology2018

Re-evaluation of pediatric

Kitiwat Khamwan, Shannon E O'Reilly, Donika Plyku, Alison Goodkind, Anders Josefsson, Xinhua Cao, Frederic H Fahey, S Ted Treves, Wesley E Bolch, George Sgouros

Open access · greenAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Physics in medicine and biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Inter-institutional variability in kidney dosimetry duringRadiological physics and technology · 2026
    Article
  2. Article
  3. Image quality and lesion detectability in low-dose pediatricEuropean journal of nuclear medicine and molecular imaging · 2021
    Article
  4. Investigating Low-Dose Image Quality in Whole-Body PediatricJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Kitiwat KhamwanThe Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University, School of Medicine, Baltimore, MD, United States of America.
Shannon E O'ReillyJ Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, United States of America.
Donika PlykuThe Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University, School of Medicine, Baltimore, MD, United States of America.
Alison GoodkindDivision of Nuclear Medicine and Molecular Imaging, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States of America.
Anders JosefssonThe Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University, School of Medicine, Baltimore, MD, United States of America.ORCID 0000-0002-0800-2305
Xinhua CaoDivision of Nuclear Medicine and Molecular Imaging, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States of America.
Frederic H FaheyDivision of Nuclear Medicine and Molecular Imaging, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States of America.
S Ted TrevesDivision of Nuclear Medicine and Molecular imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States of America.
Wesley E BolchJ Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, United States of America.ORCID 0000-0002-7175-9968
George SgourosThe Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University, School of Medicine, Baltimore, MD, United States of America.ORCID 0000-0002-9703-7082
Johns Hopkins University · USBoston Children's Hospital · USUniversity of Florida · USBrigham and Women's Hospital · US

Funding

Dose Reduction in Pediatric Molecular ImagingR01EB013558 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI FREY, ERIC C., SGOUROS, GEORGE · 2012 to 2020
$4.6M
NIBIB NIH HHS R01 EB013558
6 · The paper itself

Abstract

Because of the concerns associated with radiation exposure at a young age, there is an increased interest in pediatric absorbed dose estimates for imaging agents. Almost all reported pediatric absorbed dose estimates, however, have been determined using adult pharmacokinetic data with radionuclide S values that take into account the anatomical differences between adults and children based upon the older Cristy-Eckerman (C-E) stylized phantoms. In this work, we use pediatric model-derived pharmacokinetics to compare absorbed dose and effective dose estimates for

Indexed as

Phantoms, ImagingChildChild, PreschoolFemaleFluorodeoxyglucose F18HumansInfantInfant, NewbornMaleMonte Carlo MethodNeoplasmsOrgans at RiskPhotonsRadiation DosageRadiation ExposureRadiometryFluorodeoxyglucose F18

Identifiers

PMID30022768
PMCPMC6398606
OpenAlexW2883340894

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.