Evidence map›Paper›PMID 30022500›Full record

ArticleVox sanguinis2018

Metagenomics analysis of the virome of 300 concentrates from a Swiss platelet bank.

Francisco Brito, Samuel Cordey, Eric Delwart, Xutao Deng, Diderik Tirefort, Coralie Lemoine-Chaduc, Evgeny Zdobnov, Thomas Lecompte, Laurent Kaiser, Sophie Waldvogel-Abramowski and 1 more

Abstract read
In one paragraph

Article in Vox sanguinis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Viral Metagenomics of Blood Donors and Blood-Derived Products Using Next-Generation Sequencing.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Francisco BritoDepartment of Genetic Medicine and Development, Faculty of Medicine of Geneva, Geneva, Switzerland.
Samuel CordeyLaboratory of Virology, University Hospitals of Geneva, Geneva, Switzerland.
Eric DelwartBlood Systems Research Institute, San Francisco, CA, USA.
Xutao DengBlood Systems Research Institute, San Francisco, CA, USA.
Diderik TirefortDepartment of Internal Medicine of Medical Specialties, Faculty of Medicine of Geneva, Geneva, Switzerland.
Coralie Lemoine-ChaducBlood Transfusion Center, University Hospitals of Geneva, Geneva, Switzerland.
Evgeny ZdobnovDepartment of Genetic Medicine and Development, Faculty of Medicine of Geneva, Geneva, Switzerland.
Thomas LecompteDepartment of Internal Medicine of Medical Specialties, Faculty of Medicine of Geneva, Geneva, Switzerland.
Laurent KaiserLaboratory of Virology, University Hospitals of Geneva, Geneva, Switzerland.
Sophie Waldvogel-AbramowskiDepartment of Internal Medicine of Medical Specialties, Faculty of Medicine of Geneva, Geneva, Switzerland.
Olivier Preynat-SeauveDepartment of Internal Medicine of Medical Specialties, Faculty of Medicine of Geneva, Geneva, Switzerland.ORCID http://orcid.org/0000-0001-5364-967X

Funding

Metagenomic detection of emerging viruses in the blood supplyR01HL105770 · NHLBI · VITALANT · PI DELWART, ERIC L · 2011 to 2015
$2.4M
NHLBI NIH HHS R01 HL105770
6 · The paper itself

Abstract

BACKGROUND AND

objectivesPlatelet concentrates are frequently transfused to patients with reduced immunity. An exhaustive description of their viral content is needed to prevent unwanted infection. MATERIAL AND

methodsTo track viral sequences, a shotgun metagenomics approach was used on a bank of 300 platelets concentrates. Sequences were analysed through the diagnostics-oriented pipeline ezVIR.

resultsWe only observed viruses commonly described in healthy individuals.

conclusionHerein is reported the first viral landscape of a platelet concentrates bank.

Indexed as

next-generation sequencingplatelet concentratestransfusion-transmissible infections

Identifiers

PMID30022500
PMCPMC6338525

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.