Evidence map›Paper›PMID 30022365›Full record

ReviewClinical & experimental metastasis2018

Novel frontiers in detecting cancer metastasis.

Stanley P Leong, Carmen Ballesteros-Merino, Shawn M Jensen, Sebastian Marwitz, Carlo Bifulco, Bernard A Fox, Mojca Skoberne

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical & experimental metastasis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Introduction: Novel Frontiers in Cancer Metastasis.Clinical & experimental metastasis · 2022
    Article
  3. Review
  4. miRNA signatures in childhood sarcomas and their clinical implications.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2019
    Review
  5. Future perspectives: cancer metastases.Clinical & experimental metastasis · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Stanley P LeongCalifornia Pacific Medical Center and Research Institute, San Francisco, CA, 94115, USA. LeongSX@cpmcri.org.
Carmen Ballesteros-MerinoEarle A. Chiles Research Institute, Robert W. Franz Cancer Center, Providence Cancer Institute, Portland, OR, 97213, USA.
Shawn M JensenEarle A. Chiles Research Institute, Robert W. Franz Cancer Center, Providence Cancer Institute, Portland, OR, 97213, USA.
Sebastian MarwitzEarle A. Chiles Research Institute, Robert W. Franz Cancer Center, Providence Cancer Institute, Portland, OR, 97213, USA.
Carlo BifulcoTranslational Digital and Molecular Pathology, Earle A. Chiles Research Institute, Robert W. Franz Cancer Center, Providence Cancer Institute, Portland, OR, 97213, USA.
Bernard A FoxEarle A. Chiles Research Institute, Robert W. Franz Cancer Center, Providence Cancer Institute, Portland, OR, 97213, USA.
Mojca SkoberneGritstone Oncology, Cambridge, MA, 02139, USA.
Providence Portland Medical Center · USCalifornia Pacific Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer microenvironment is the critical battle ground between the cancer cells and host response. Thus, more emphasis is directed to study the relationship between cancer cells and the stromal cells. Multiplex microscopy is an emerging technique in which multiple cell populations within the cancer microenvironment may be stained so that spatial relationship between cancer cells and, in particular, the immune cells may be studied during different stages of cancer development. Recent discovery of mutational burden and neoantigens in cancer has opened new landscapes in the interaction of host immune cells and cancer neoantigens. The emerging role of miRNAs may become an added dimension to study cancer beyond traditional pathway of DNA directed RNA being associated with the malignant behavior of cancer. Circulating tumor cells, cancer markers and ctDNA can be used as markers for circulating cancer cells in the blood. Further studies are needed to validate if liquid biopsy of cancer may become a routine clinical tool to screen cancer or follow patients for recurrence or responses to treatment.

Indexed as

Antigens, NeoplasmBiomarkers, TumorCirculating Tumor DNAHumansLiquid BiopsyMutationNeoplasm MetastasisNeoplasm Recurrence, LocalNeoplasmsNeoplastic Cells, CirculatingTumor MicroenvironmentAntigens, NeoplasmBiomarkers, TumorCirculating Tumor DNACancer microenvironmentCancer neoantigensCirculating tumor cellsImmune cellsMicroRNA

Identifiers

PMID30022365
OpenAlexW2884197203

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.