ReviewClinical autonomic research : official journal of the Clinical Autonomic Research Society2019
Autonomic dysfunction in the neurological intensive care unit.
Review in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 35 citations in OpenAlex.
- Ultrafiltration in the critically ill patient: a framework for personalized care.Critical care (London, England) · 2026Review
- Demise of the Milwaukee Protocol for Rabies.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025Article
- Artificial intelligence in pediatric intensive care: unlocking integrated monitoring for autonomic nervous system dysregulation.Pediatric research · 2025Article
- Heart Rate Variability and Cerebral Autoregulation in Patients with Traumatic Brain Injury with Paroxysmal Sympathetic Hyperactivity Syndrome.Neurocritical care · 2025Article
- Diagnosis and management of paroxysmal sympathetic hyperactivity: a narrative review of recent literature.European journal of medical research · 2025Review
- Application of sugar-free cola solution based on the ICOCFAS score in oral care of non-artificial airway patients with severe neurological conditions.Frontiers in medicine · 2025Article
- Exploration of simultaneous transients between cerebral hemodynamics and the autonomic nervous system using windowed time-lagged cross-correlation matrices: a CENTER-TBI study.Acta neurochirurgica · 2024Article
- Management and outcome of adult generalized tetanus in a Chinese tertiary hospital.Frontiers in public health · 2024Observational
- Feasibility study of the Nox-T3 device to detect swallowing and respiration pattern in neurologically impaired patients in the acute phase.Scientific reports · 2023Article
- Paroxysmal Sympathetic Hyperactivity in Neurocritical Children: A Pilot Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022Article
- Detecting Sepsis in Patients with Severe Subarachnoid Hemorrhage during Critical Care.Journal of clinical medicine · 2022Article
- Relationship Between Baroreflex and Cerebral Autoregulation in Patients With Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage.Frontiers in neurology · 2021Article
- Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autonomic dysfunction is common in neuro-critical care patients and may compromise the function of various organs. Among the many diseases causing or being associated with autonomic dysfunction are traumatic brain injury, cerebrovascular diseases, epilepsy, Guillain-Barré syndrome (GBS), alcohol withdrawal syndrome, botulism and tetanus, among many others. Autonomic dysfunction may afflict various organs and may involve hyper- or hypo-activity of the sympathetic or parasympathetic system. In this short overview, we address only a small number of neuro-intensive care diseases with autonomic dysfunction. In GBS, autonomic dysfunction is frequent and may account for increased mortality rates; rapid changes between sympathetic and parasympathetic hypo- or hyper-activity may cause life-threatening cardiovascular complications. Paroxysmal sympathetic hyperactivity occurs after brain injury, hypoxia and cerebrovascular and other events, causes paroxysmal tachycardia, hypertension, tachypnoea and hyperthermia and is associated with a poorer prognosis and prolonged intensive care treatment. Other, at times life-threatening autonomic complications with exaggerated sympathetic activity and compromised baroreflex sensitivity arise during the alcohol withdrawal syndrome triggered by abrupt cessation of alcohol consumption. Botulism and tetanus are examples of life-threatening autonomic dysfunction caused by bacterial neurotoxins. Common neurological diseases, such as epilepsy, stroke or subarachnoid haemorrhage, are also associated with autonomic dysfunction that can on occasion cause critical deterioration of disease severity and prognosis.
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