Evidence map›Paper›PMID 30022297›Full record

ArticleClinical journal of gastroenterology2018

Gastric adenocarcinoma coexisting with a reddish semipedunculated polyp arising from Helicobacter pylori-negative normal gastric mucosa: a report of two cases.

Yoshiaki Isono, Youichirou Baba, Katsumi Mukai, Hiroki Asakawa, Kenji Nose, Satomi Tsuruga, Tomomasa Tochio, Hiroaki Kumazawa, Hiroki Tanaka, Shimpei Matsusaki and 4 more

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Clinical journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Grasp-and-lift technique - Novel cold forceps polypectomy technique for a gastric foveolar-type adenoma.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. UEG Week 2019 Poster Presentations.United European gastroenterology journal · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yoshiaki IsonoDepartment of Gastroenterology, Suzuka General Hospital, 1275-53 Yamanohana, Yasuzuka, Suzuka, Mie, Japan. yoshiaki.isono@miekosei.or.jp.ORCID http://orcid.org/0000-0003-4290-7148
Youichirou BabaDepartment of Pathology, Suzuka General Hospital, 1275-53 Yamanohana, Yasuzuka, Suzuka, Mie, Japan.
Katsumi MukaiDepartment of Gastroenterology, Suzuka General Hospital, 1275-53 Yamanohana, Yasuzuka, Suzuka, Mie, Japan.
Hiroki AsakawaDepartment of Gastroenterology, Suzuka General Hospital, 1275-53 Yamanohana, Yasuzuka, Suzuka, Mie, Japan.
Kenji NoseDepartment of Gastroenterology, Suzuka General Hospital, 1275-53 Yamanohana, Yasuzuka, Suzuka, Mie, Japan.
Satomi TsurugaDepartment of Gastroenterology, Suzuka General Hospital, 1275-53 Yamanohana, Yasuzuka, Suzuka, Mie, Japan.
Tomomasa TochioDepartment of Gastroenterology, Suzuka General Hospital, 1275-53 Yamanohana, Yasuzuka, Suzuka, Mie, Japan.
Hiroaki KumazawaDepartment of Gastroenterology, Suzuka General Hospital, 1275-53 Yamanohana, Yasuzuka, Suzuka, Mie, Japan.
Hiroki TanakaDepartment of Gastroenterology, Suzuka General Hospital, 1275-53 Yamanohana, Yasuzuka, Suzuka, Mie, Japan.
Shimpei MatsusakiDepartment of Gastroenterology, Suzuka General Hospital, 1275-53 Yamanohana, Yasuzuka, Suzuka, Mie, Japan.
Tomohiro SaseDepartment of Gastroenterology, Suzuka General Hospital, 1275-53 Yamanohana, Yasuzuka, Suzuka, Mie, Japan.
Tomonori SaitoDepartment of Gastroenterology, Suzuka General Hospital, 1275-53 Yamanohana, Yasuzuka, Suzuka, Mie, Japan.
Hiroshi OkanoDepartment of Gastroenterology, Suzuka General Hospital, 1275-53 Yamanohana, Yasuzuka, Suzuka, Mie, Japan.
Hideki ToyodaHappy GI Clinic, 2-9-33 Honmachi, Kameyama, Mie, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We experienced two cases of adenocarcinoma coexisting with a hyperplastic polyp arising from Helicobacter pylori-negative normal gastric mucosa. The first case was of a 59-year-old man. Esophagogastroduodenoscopy revealed a protruding lesion measuring 4 mm in diameter on the greater curvature of the middle gastric body. The second case was of a 47-year-old man. Esophagogastroduodenoscopy showed a protruding lesion measuring 5 mm located at the greater curvature of the upper gastric body. The absence of atrophic changes in the entire gastric mucosa was confirmed endoscopically in both cases. Multiple H. pylori tests were all negative. Endoscopically, these protruding lesions appeared as reddish, semipedunculated polyps. Hyperplastic polyps were suspected based on white light endoscopic findings. Magnified endoscopy with narrow band imaging could not predict the coexistence of cancer. However, histopathological examination of the resected specimen revealed focal cancer at the surface of the gastric hyperplastic polyps. Considering the possibility that cancer may be coexisting in polyps, when reddish polyps are detected in H. pylori-negative normal gastric mucosa, it is important to perform a biopsy, or a careful follow-up endoscopy.

Indexed as

AdenocarcinomaBiopsyEndoscopy, Digestive SystemGastric MucosaHelicobacter pyloriHumansMaleMiddle AgedNeoplasms, Multiple PrimaryPolypsStomach NeoplasmsGastric cancerGastric hyperplastic polypHelicobacter pylori-negative

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.