Evidence map›Paper›PMID 30022263›Full record

ArticleApplied microbiology and biotechnology2018

Immune responses induced by recombinant Lactobacillus plantarum expressing the spike protein derived from transmissible gastroenteritis virus in piglets.

Yu-Bei Jin, Wen-Tao Yang, Chun-Wei Shi, Bo Feng, Ke-Yan Huang, Guang-Xun Zhao, Qiong-Yan Li, Jing Xie, Hai-Bin Huang, Yan-Long Jiang and 5 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied microbiology and biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Article
  3. International journal of molecular sciences · 2025
    Article
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  6. Frontiers in immunology · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Frontiers in microbiology · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Yu-Bei JinCollege of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, 2888 Xincheng Street, Changchun, 130118, China.
Wen-Tao YangCollege of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, 2888 Xincheng Street, Changchun, 130118, China.
Chun-Wei ShiCollege of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, 2888 Xincheng Street, Changchun, 130118, China.
Bo FengCollege of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, 2888 Xincheng Street, Changchun, 130118, China.
Ke-Yan HuangCollege of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, 2888 Xincheng Street, Changchun, 130118, China.
Guang-Xun ZhaoCollege of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, 2888 Xincheng Street, Changchun, 130118, China.
Qiong-Yan LiCollege of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, 2888 Xincheng Street, Changchun, 130118, China.
Jing XieCollege of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, 2888 Xincheng Street, Changchun, 130118, China.
Hai-Bin HuangCollege of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, 2888 Xincheng Street, Changchun, 130118, China.
Yan-Long JiangCollege of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, 2888 Xincheng Street, Changchun, 130118, China.
Jian-Zhong WangCollege of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, 2888 Xincheng Street, Changchun, 130118, China.
Guan WangCollege of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, 2888 Xincheng Street, Changchun, 130118, China.
Yuan-Huan KangCollege of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, 2888 Xincheng Street, Changchun, 130118, China.
Gui-Lian YangCollege of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, 2888 Xincheng Street, Changchun, 130118, China. yangguilian@jlau.edu.cn.
Chun-Feng WangCollege of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, 2888 Xincheng Street, Changchun, 130118, China. wangchunfeng@jlau.edu.cn.
Jilin Agricultural University · CN

Funding

National Natural Science Foundation of China 31672528
6 · The paper itself

Abstract

Transmissible gastroenteritis coronavirus (TGEV) is one of the most severe threats to the swine industry. In this study, we constructed a suite of recombinant Lactobacillus plantarum with surface displaying the spike (S) protein coming from TGEV and fused with DC cells targeting peptides (DCpep) to develop an effective, safe, and convenient vaccine against transmissible gastroenteritis. Our research results found that the recombinant Lactobacillus plantarum (NC8-pSIP409-pgsA-S-DCpep) group expressing S fused with DCpep could not only significantly increase the percentages of MHC-II

Indexed as

AnimalsAntibodies, ViralBacterial ProteinsB-LymphocytesGastroenteritis, Transmissible, of SwineImmunoglobulin A, SecretoryImmunoglobulin GIntracellular Signaling Peptides and ProteinsLactiplantibacillus plantarumSwineT-LymphocytesTransmissible gastroenteritis virusViral VaccinesAntibodies, ViralBacterial ProteinsImmunoglobulin A, SecretoryImmunoglobulin GIntracellular Signaling Peptides and ProteinsViral VaccinesB cellsDCpepImmune responseLactobacillus plantarumOral immunizationTGEV S protein

Identifiers

PMID30022263
PMCPMC7080080
OpenAlexW2884069532

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.