ArticleNature2018
Controlling an organic synthesis robot with machine learning to search for new reactivity.
Article in Nature, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 175 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
175 citing papers in PubMed.
- AI-Driven Synthesis in Medicinal Chemistry: Integrating Large Language Models, Robotic Automation, and Sustainability Metrics to Accelerate Drug Discovery.Medicinal research reviews · 2026Review
- Competition-Derived Relative Reactivity and 3D Electronic-State Analysis of Site- and Facial Selectivity in NaBHJACS Au · 2026Article
- Big Data and Artificial Intelligence in Cancer Drug Discovery: Promise, Challenges, and Emerging Opportunities.Cancers · 2026Review
- High-throughput reaction screening using acoustic ejection mass spectrometry.Nature protocols · 2026Review
- The past, present and future of self-driving laboratories.Nature reviews. Chemistry · 2026Review
- AutoLabs: cognitive multi-agent systems with self-correction for autonomous chemical experimentation.Scientific reports · 2026Article
- A machine learning perspective on three decades of methanol synthesis: research framework and experimental operation insights.Communications engineering · 2026Article
- Machine learning assisted technoeconomic assessment of microalgal biofuel production pathways.Bioprocess and biosystems engineering · 2026Review
- Development of green purification process for piperazine-type drugs: a case study of quetiapine process development.RSC advances · 2026Article
- Staged Diversity-Constrained Machine Learning for High-Dimensional Reaction Condition Optimization.Angewandte Chemie (International ed. in English) · 2026Article
- Yield Prediction of Organic Reactions in Biased Data Sets via Positive-Unlabeled Learning.Journal of the American Chemical Society · 2026Article
- Chemputer and chemputation-A universal chemical compound synthesis machine.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- AI and Robotics Advancement in Analytical Mineral Characterization and Mining Processes: A Review and Research Trends Analysis.Topics in current chemistry (Cham) · 2026Review
- Extracting Mechanistic Information from an Open Data Set for a Pharma-Relevant Suzuki-Miyaura Cross-Coupling Reaction.Organic process research & development · 2026Article
- Autonomous microfluidic labs: progress and prospects.Lab on a chip · 2026Review
- Parallelized contactless microfluidic dispenser with superhydrophobic nozzles for scalable combinatorial screening.Biomicrofluidics · 2026Article
- The ADePT framework for assessing autonomous laboratory robotics.Communications chemistry · 2026Review
- AI-driven robotic crystal explorer for rapid polymorph identification.Digital discovery · 2026Article
- Utilizing Similarity Measures to Map Chemical Reactivity.Angewandte Chemie (International ed. in English) · 2026Article
- Modelling and estimation of chemical reaction yields from high-throughput experiments.Communications chemistry · 2026Article
115 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Erratum issued
- Erratum issued
Authors and funding
5 authors.
Funding
Abstract
The discovery of chemical reactions is an inherently unpredictable and time-consuming process
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.