Evidence map›Paper›PMID 30021952›Full record

ArticleCancers2018

Pancreatic Cancer Related Health Disparities: A Commentary.

Lisa Scarton, Saunjoo Yoon, Sungho Oh, Edward Agyare, Jose Trevino, Bo Han, Eunsook Lee, Veronica Wendy Setiawan, Jennifer B Permuth, Thomas D Schmittgen and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.6field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
  5. Article
  6. Diabetes and pancreatic cancer risk in a multiracial cohort.Diabetic medicine : a journal of the British Diabetic Association · 2024
    Article
  7. Article
  8. Unraveling Racial Disparities in Supportive Care Medication Use among End-of-Life Pancreatic Cancer Patients: Focus on Pain Management and Psychiatric Therapies.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Lisa ScartonDepartment of Family, Community and Health System Science, 1225 Center Drive, P. O. Box 100187, Gainesville, FL 32610, USA. lscarton@ufl.edu.ORCID 0000-0003-1255-0811
Saunjoo YoonDepartment of Biobehavioral Nursing Science, College of Nursing, University of Florida, Gainesville, FL 32610, USA. yoon@UFL.EDU.ORCID 0000-0001-5669-8709
Sungho OhDepartment of Biobehavioral Nursing Science, College of Nursing, University of Florida, Gainesville, FL 32610, USA. sungho.oh@ufl.edu.
Edward AgyareDepartment of Pharmaceutics, College of Pharmacy & Pharmaceutical Sciences, Florida Agricultural and Mechanical University, Tallahassee, FL 32301, USA. edward.agyare@famu.edu.
Jose TrevinoDepartment of Surgery, College of Medicine, University of Florida, Gainesville, FL 32610, USA. Jose.Trevino@surgery.ufl.edu.
Bo HanDepartment Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA. bohan@usc.edu.
Eunsook LeeDepartment of Pharmacology and Toxicology, College of Pharmacy & Pharmaceutical Sciences, Florida Agricultural and Mechanical University, Tallahassee, FL 32301, USA. eunsook.lee@famu.edu.
Veronica Wendy SetiawanDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA. vsetiawa@med.usc.edu.
Jennifer B PermuthDepartments of Cancer Epidemiology and Gastroinestinal Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA. Jenny.Permuth@moffitt.org.
Thomas D SchmittgenDepartment of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA. TSchmittgen@cop.ufl.edu.
Folakemi G OdedinaDepartment of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA. FOdedina@cop.ufl.edu.
Diana J WilkieDepartment of Biobehavioral Nursing Science, College of Nursing, University of Florida, Gainesville, FL 32610, USA. diwilkie@ufl.edu.ORCID 0000-0002-3954-8933
University of Florida · USFlorida Agricultural and Mechanical University · USUniversity of Southern California · USMoffitt Cancer Center · US

Funding

Tissue Modeling & Drug Development Shared Resources CoreU54CA233444 · NCI · UNIVERSITY OF FLORIDA · PI Chanita A. Hughes-Halbert, Tianze Jiao · 2018 to 2026
$12.1M
Tissue Modeling CoreU54CA233396 · NCI · FLORIDA AGRICULTURAL AND MECHANICAL UNIV · PI Ukamaka D. Smith · 2018 to 2026
$9.8M
Mechanisms associated with neuroprotection from Mn-induced neurotoxicity.R01ES031282 · NIEHS · FLORIDA AGRICULTURAL AND MECHANICAL UNIV · PI LEE, EUNSOOK YU · 2020 to 2025
$2.4M
Mechanism of manganese-induced impairment of astrocytic glutamate transportersR01ES024756 · NIEHS · MEHARRY MEDICAL COLLEGE · PI LEE, EUN SOOK YU · 2015 to 2019
$1.8M
Training and Education ProgramP20CA192992 · NCI · UNIVERSITY OF FLORIDA · PI ODEDINA, FOLAKEMI T · 2014 to 2017
$662k
NCI NIH HHS P20 CA192992NCI NIH HHS U54 CA233396NCI NIH HHS U54 CA233444NIEHS NIH HHS R01 ES024756NIEHS NIH HHS R01 ES031282
6 · The paper itself

Abstract

We summarize the risk factors that may significantly contribute to racial disparities in pancreatic cancer, which is now the third leading cause of cancer deaths and projected to be second around 2030 in 12 years. For decades, the incidence rate of pancreatic cancer among Blacks has been 30% to 70% higher than other racial groups in the United States and the 5-year survival rate is approximately 5%. Diabetes and obesity have been identified as potentially predisposing factors to pancreatic cancer and both are more common among Blacks. Smoking continues to be one of the most important risk factors for pancreatic cancer and smoking rates are higher among Blacks compared to other racial groups. The overall risk of pancreatic cancer due to changes in DNA is thought to be the same for most racial groups; however, DNA methylation levels have been observed to be significantly different between Blacks and Whites. This finding may underlie the racial disparities in pancreatic cancer. Identification and prevention of these factors may be effective strategies to reduce the high incidence and mortality rates for pancreatic cancer among Blacks.

Indexed as

pancreatic cancerracial disparities

Identifiers

PMID30021952
PMCPMC6070801
OpenAlexW2883703721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.