Evidence map›Paper›PMID 30021935›Full record

ArticleNanomaterials (Basel, Switzerland)2018

In Vitro Cytotoxicity and Morphological Assessments of GO-ZnO against the MCF-7 Cells: Determination of Singlet Oxygen by Chemical Trapping.

Fozia Shaheen, Muhammad Hammad Aziz, Mahvish Fatima, Muhammad Ajmal Khan, Faisal Ahmed, Riaz Ahmad, Muhammad Ashfaq Ahmad, Turki S Alkhuraiji, Muhammad Waseem Akram, Rizwan Raza and 1 more

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Eco-Friendly Synthesis of SnONanomaterials (Basel, Switzerland) · 2021
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fozia ShaheenDepartment of Physics, Government College (GC) University, Lahore 54000, Pakistan. foziashaheen@gcu.edu.pk.
Muhammad Hammad AzizDepartment of Physics, COMSATS Institute of Information and Technology, Lahore 54000, Pakistan. hammadaziz@ciitlahore.edu.pk.
Mahvish FatimaDepartment of Physics, University of Lahore, 54000 Lahore, Pakistan. mahvish.fatima@phys.uol.edu.pk.
Muhammad Ajmal KhanDepartment of Physics, COMSATS Institute of Information and Technology, Lahore 54000, Pakistan. ajmalkhan@ciitlahore.edu.pk.
Faisal AhmedDepartment of Chemical Engineering, COMSATS Institute of Information and Technology, Lahore 54000, Pakistan. faisalahmed@ciitlahore.edu.pk.
Riaz AhmadThe Centre for Advanced Studies in Physics (CASP), Government College (GC) University, Church Road, Lahore 54000, Pakistan. ahriaz@gcu.edu.pk.
Muhammad Ashfaq AhmadDepartment of Physics, COMSATS Institute of Information and Technology, Lahore 54000, Pakistan. maahmad@ciitlahore.edu.pk.
Turki S AlkhuraijiKing Abdulaziz City for Science and Technology-KACST, Nuclear Science Research Institute, P.O. BOX 6086, 11442 Riyadh, Saudi Arabia. khuraiji@kacst.edu.sa.
Muhammad Waseem AkramInstitute of Fundamental and Frontier Science, University of Electronic Science and Technology of China, Chengdu 610054, China. waseem.physicist@gmail.com.
Rizwan RazaDepartment of Physics, COMSATS Institute of Information and Technology, Lahore 54000, Pakistan. rizwanraza@ciitlahore.edu.pk.
Syed Mansoor AliDepartment of Physics and Astronomy, College of Science, King Saud University, Riyadh 11451, Saudi Arabia. mansoor_phys@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Graphene-based materials have attracted considerable interest owing to their distinctive characteristics, such as their biocompatibility in terms of both their physical and intrinsic chemical properties. The use of nanomaterials with graphene as a biocompatible agent has increased due to an uptick in dedication from biomedical investigators. Here, GO-ZnO was characterized by X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), ultraviolet-visible (UV-Vis) spectroscopy, energy dispersive X-ray analysis (EDAX), and Raman spectroscopy for structural, morphological, and elemental analysis. The toxic extent of GO-ZnO was noted by a methyl-thiazole-tetrazolium (MTT), while cellular morphology was observed towards the MCF-7 cells using an inverted microscope at magnification 40×. The cytotoxic effect of GO-ZnO investigated the cell viability reduction in a dose-dependent manner, as well as prompted the cell demise/destruction in an apoptotic way. Moreover, statistical analysis was performed on the experimental outcomes, with

Indexed as

cellular morphologycytotoxicitygraphene oxide (GO)reactive oxygen species (ROS)

Identifiers

PMID30021935
PMCPMC6070898

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.