Evidence map›Paper›PMID 30021904›Full record

ArticleJournal of virology2018

Enhancer Control of MicroRNA miR-155 Expression in Epstein-Barr Virus-Infected B Cells.

C David Wood, Thomas Carvell, Andrea Gunnell, Opeoluwa O Ojeniyi, Cameron Osborne, Michelle J West

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Role of miR-155 in inflammatory autoimmune diseases: a comprehensive review.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

C David WoodSchool of Life Sciences, University of Sussex, Falmer, Brighton, United Kingdom.
Thomas CarvellSchool of Life Sciences, University of Sussex, Falmer, Brighton, United Kingdom.
Andrea GunnellSchool of Life Sciences, University of Sussex, Falmer, Brighton, United Kingdom.
Opeoluwa O OjeniyiSchool of Life Sciences, University of Sussex, Falmer, Brighton, United Kingdom.
Cameron OsborneDepartment of Medical and Molecular Genetics, King's College London School of Medicine, Guy's Hospital, London, United Kingdom.
Michelle J WestSchool of Life Sciences, University of Sussex, Falmer, Brighton, United Kingdom m.j.west@sussex.ac.uk.
University of Sussex · GBKing's College London · GB

Funding

Medical Research Council MR/K01952X/1
6 · The paper itself

Abstract

The oncogenic microRNA (miRNA) miR-155 is the most frequently upregulated miRNA in Epstein-Barr virus (EBV)-positive B cell malignancies and is upregulated in other nonviral lymphomas. Both EBV nuclear antigen 2 (EBNA2) and the B cell transcription factor interferon regulatory factor 4 (IRF4) are known to activate transcription of the host cell gene from which miR-155 is processed (

Indexed as

Enhancer Elements, GeneticGene Expression RegulationB-LymphocytesCells, CulturedEpstein-Barr Virus InfectionsEpstein-Barr Virus Nuclear AntigensHerpesvirus 4, HumanHumansInterferon Regulatory Factor-4Interferon Regulatory FactorsMicroRNAsPromoter Regions, GeneticViral ProteinsEBNA-2 protein, Human herpesvirus 4Epstein-Barr Virus Nuclear AntigensInterferon Regulatory Factor-4Interferon Regulatory FactorsMicroRNAsMIRN155 microRNA, humanViral ProteinsEBNA2enhancerEpstein-Barr virusmiR-155transcriptional regulation

Identifiers

PMID30021904
PMCPMC6146817
OpenAlexW2889626186

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.