Evidence map›Paper›PMID 30021890›Full record

ArticleJournal of virology2018

Growth-Adaptive Mutations in the Ebola Virus Makona Glycoprotein Alter Different Steps in the Virus Entry Pathway.

John B Ruedas, Catherine E Arnold, Gustavo Palacios, John H Connor

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

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  12. Frontiers in microbiology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

John B RuedasDepartment of Microbiology, Boston University School of Medicine, Boston, Massachusetts, USA jruedas@bu.edu jhconnor@bu.edu.
Catherine E ArnoldCenter for Genome Sciences, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.ORCID https://orcid.org/0000-0002-1635-4941
Gustavo PalaciosCenter for Genome Sciences, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.ORCID https://orcid.org/0000-0001-5062-1938
John H ConnorDepartment of Microbiology, Boston University School of Medicine, Boston, Massachusetts, USA jruedas@bu.edu jhconnor@bu.edu.ORCID https://orcid.org/0000-0002-8867-7256
Boston University · USUnited States Army Medical Research Institute of Infectious Diseases · US

Funding

Resource for Biocomputing Visualization and InformaticsP41GM103311 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2012 to 2017
$8.2M
Development of Near Real-Time, Multiplexed Diagnostics for Viral Hemorrhagic FeveR01AI096159 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CONNOR, JOHN H · 2011 to 2015
$4.8M
Genetic probing of residues involved in ebolavirus glycoprotein entryR21AI135517 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CONNOR, JOHN H · 2018 to 2019
$454k
NIAID NIH HHS R01 AI096159NIAID NIH HHS R21 AI135517NIGMS NIH HHS P41 GM103311
6 · The paper itself

Abstract

The

Indexed as

EbolavirusMutationViral Envelope ProteinsVirus InternalizationAnimalsCathepsin BChlorocebus aethiopsHumansProtein Structure, SecondaryVero CellsCathepsin BCTSB protein, humanenvelope glycoprotein, Ebola virusViral Envelope Proteinscathepsin BEbola virusfusion loop mutationsglycoprotein mutationheptad repeat mutationstissue culture adaptationvirus entry

Identifiers

PMID30021890
PMCPMC6146795
OpenAlexW2884952478

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.