ArticleLipids in health and disease2018
Lipid profiles in adolescents with and without asthma: Korea National Health and nutrition examination survey data.
Article in Lipids in health and disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 77 citations in OpenAlex.
- Associations of asthma with obesity phenotypes and dyslipidemia among Korean adolescents: a secondary data analysis of the Eighth Korea National Health and Nutrition Examination Survey.Child health nursing research · 2026Article
- Quantifying the interaction between adiposity and hyperglycemia on incident asthma among youth.BMC public health · 2026Article
- Low socioeconomic status, insulin resistance, asthma, and depression: A syndemic framework in Brazilian adolescents.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026Article
- Effects of metabolic syndrome on pulmonary infection in pediatric bronchial asthma: a narrative review.Frontiers in pediatrics · 2026Review
- Mediating role of basophils in the triacylglycerol-asthma link: a Mendelian randomization study.3 Biotech · 2025Article
- Impact of diabetes duration and hyperglycemia on the progression of diabetic kidney disease: Insights from the KNHANES 2019-2021.World journal of diabetes · 2025Article
- Comorbidities associated with adult asthma according to severity: analysis of data from the National Health Insurance Sharing Service.Journal of thoracic disease · 2025Article
- Repurposing lipid-lowering drugs on asthma and lung function: evidence from a genetic association analysis.Journal of translational medicine · 2024Article
- Not Only Metabolic Complications of Childhood Obesity.Nutrients · 2024Review
- The investigation of the role of oral-originatedFrontiers in microbiology · 2024Article
- Causal relationship between PCSK9 inhibitor and autoimmune diseases: a drug target Mendelian randomization study.Arthritis research & therapy · 2023Article
- Association between dyslipidemia and asthma in children: a systematic review and multicenter cohort study using a common data model.Clinical and experimental pediatrics · 2023Article
- High density lipoprotein-cholesterol is inversely associated with blood eosinophil counts among asthmatic adults in the USA: NHANES 2011-2018.Frontiers in immunology · 2023Article
- Article
- A new perspective on cholesterol in pediatric health: association of vitamin D metabolism, respiratory diseases, and mental health problems.Clinical and experimental pediatrics · 2022Article
- Clustering patterns of metabolic syndrome: A cross-sectional study in children and adolescents in Kyiv.Frontiers in pediatrics · 2022Article
- Are lipid ratios and triglyceride-glucose index associated with critical care outcomes in COVID-19 patients?PloS one · 2022Article
- TG/HDL-C Ratio Independent of Obesity Associates with Airflow Obstruction in Children with Asthma.Indian journal of pediatrics · 2022Article
- Asthma and obesity: endotoxin another insult to add to injury?Clinical science (London, England : 1979) · 2021Review
- Lipid Nutrition in Asthma.Cell biochemistry and biophysics · 2021Review
Corrections and comments
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Authors and funding
9 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMetabolic syndrome and dyslipidemia contribute to the development of a pro-inflammatory state in asthma. However, studies investigating the association between asthma and dyslipidemia have reported conflicting results. This study aimed to uncover the relationship between asthma and lipid profiles in adolescents using a national health and nutrition survey.
methodsThis cross-sectional study analyzed the 2010-2012 Korea National Health and Nutrition Examination Survey data and included 2841 subjects aged 11-18 years with fasting blood sample data. Serum total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) levels were analyzed. We compared asthma prevalence between high-risk and low-risk lipid groups.
resultsThere were 123 adolescents with asthma and 2718 without asthma (controls). The TC/HDL-C ratio, LDL-C/HDL-C ratio, and non-HDL-C levels were significantly higher in the asthma group than in the non-asthma group (P < 0.05). The high-risk groups displayed significantly higher asthma prevalence with higher TC, TG, LDL-C, and non-HDL-C levels and TG/HDL-C ratio than the low-risk groups (P < 0.05). After adjusting for potential confounding factors, the high-risk groups were associated with asthma according to their higher TC levels (adjusted odds ratio, 1.69; 95% confidence interval, 1.012-2.822) and TG/HDL-C ratios (adjusted odds ratio, 1.665; 95% confidence interval, 1.006-2.756).
conclusionsAsthma prevalence was greater in adolescents with a high TC level and TG/HDL-C ratio. In addition to the standard lipid profile, elevated TG/HDL-C ratio can be used as a useful additional lipid measure to evaluate interactions between dyslipidemia and asthma.
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