Evidence map›Paper›PMID 30021509›Full record

ArticleBMC family practice2018

Novel oral anticoagulants in primary care in patients with atrial fibrillation: a cross-sectional comparison before and after their introduction.

Simon Schwill, Katja Krug, Frank Peters-Klimm, Jan van Lieshout, Gunter Laux, Joachim Szecsenyi, Michel Wensing

Open access · goldAbstract read
In one paragraph

Article in BMC family practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. [Changes in Prescription Patterns of Oral Anticoagulants in Family Practices after Marketing Approval of Direct Oral Anticoagulants].Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)) · 2023
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Simon SchwillDepartment of General Practice and Health Services Research, University Hospital Heidelberg, Heidelberg, Germany. simon.schwill@med.uni-heidelberg.de.
Katja KrugDepartment of General Practice and Health Services Research, University Hospital Heidelberg, Heidelberg, Germany.
Frank Peters-KlimmDepartment of General Practice and Health Services Research, University Hospital Heidelberg, Heidelberg, Germany.
Jan van LieshoutRadboud Institute of Health Sciences, Radboud University Medical Centre, Nijmegen, Netherlands.
Gunter LauxDepartment of General Practice and Health Services Research, University Hospital Heidelberg, Heidelberg, Germany.
Joachim SzecsenyiDepartment of General Practice and Health Services Research, University Hospital Heidelberg, Heidelberg, Germany.
Michel WensingDepartment of General Practice and Health Services Research, University Hospital Heidelberg, Heidelberg, Germany.
Heidelberg University · DEUniversity Hospital Heidelberg · DERadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNovel oral anticoagulation (NOAC) has been introduced in recent years, but data on use in atrial fibrillation (AF) in primary care setting is scarce. In Germany, General Practitioners are free to choose type of oral anticoagulation (OAC) in AF. Our aim was to explore changes in prescription-rates of OAC in German primary care before and after introduction of NOAC on the market.

methodsData of a representative morbidity registration project in primary care in Germany (CONTENT) were analysed. Patients with AF in 2011 or 2014 were included (before and after broad market authorization of NOAC, respectively). We defined three independent groups: patients from 2011 without follow-up (group A), patients from 2014 but without previous record in 2011 (group B) and patients with AF and records in 2011 and 2014 (group C).

results2642 patients were included. Group A (n = 804) and B (n = 755) were comparable regarding patient characteristics. 87.3% of group A and 84.8% of group B had CHA

conclusionsIn summary, our study showed a significant increase of OAC over time, which is fostered by the use of NOAC but with a stable rate of VKA and a sharp decrease of ASA. Patients on VKA are rarely switched to NOAC, but new patients with AF are more likely to receive NOAC.

Indexed as

Primary Health CareAdolescentAdultAgedAged, 80 and overAnticoagulantsAspirinAtrial FibrillationCross-Sectional StudiesDabigatranFemaleGermanyHumansMaleMiddle AgedPhenprocoumonAnticoagulantsapixabanAspirinDabigatranPhenprocoumonPlatelet Aggregation InhibitorsPyrazolesPyridonesRivaroxabanAtrial fibrillationNovel oral anticoagulantsOral anticoagulationStroke preventionVitamin K antagonists

Identifiers

PMID30021509
PMCPMC6052679
OpenAlexW2884066430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.