Evidence map›Paper›PMID 30021156›Full record

ArticleCell reports2018

The Ubiquitin Ligase Adaptor NDFIP1 Selectively Enforces a CD8

Mayura V Wagle, Julia M Marchingo, Jason Howitt, Seong-Seng Tan, Christopher C Goodnow, Ian A Parish

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Increase of Dose Associated With Decrease in Protection Against Controlled Human Malaria Infection by PfSPZ Vaccine in Tanzanian Adults.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Trial
  3. Review
  4. Article
  5. Article
  6. The CD8Immunity · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

Mayura V WagleJohn Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia; Garvan Institute of Medical Research, Sydney, NSW, Australia.
Julia M MarchingoDivision of Immunology, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia.
Jason HowittThe Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, Australia; Department of Health and Medical Sciences, Swinburne University, Melbourne, VIC, Australia.
Seong-Seng TanThe Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, Australia.
Christopher C GoodnowJohn Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia; Garvan Institute of Medical Research, Sydney, NSW, Australia; St Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia. Electronic address: c.goodnow@garvan.org.au.
Ian A ParishJohn Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia; Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia. Electronic address: ian.parish@petermac.org.
Australian National University · AUFlorey Institute of Neuroscience and Mental Health · AUPeter MacCallum Cancer Centre · AUSwinburne University of Technology · AUUniversity of Melbourne · AUUNSW Sydney · AU

Funding

Systems Biology CoreU19AI100627 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI ULEVITCH, RICHARD J · 2012 to 2021
$49.1M
NIAID NIH HHS U19 AI100627
6 · The paper itself

Abstract

Escape from peripheral tolerance checkpoints that control cytotoxic CD8

Indexed as

Immune ToleranceAnimalsAntigensAutoantigensCarrier ProteinsCD8-Positive T-LymphocytesCell DifferentiationCell ProliferationClonal AnergyDose-Response Relationship, ImmunologicIntercellular Signaling Peptides and ProteinsMembrane ProteinsMice, Inbred C57BLMutationPancreasPeptidesAntigensAutoantigensCarrier ProteinsIntercellular Signaling Peptides and ProteinsMembrane ProteinsNdfip1 protein, mousePeptidesReceptors, Antigen, T-CellanergyautoimmunitycheckpointNdfip1peripheral toleranceT cellubiquitin ligases

Identifiers

PMID30021156
PMCPMC6112980
OpenAlexW2882991826

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.