Evidence map›Paper›PMID 30020437›Full record

ArticleDatabase : the journal of biological databases and curation2018

Extracting chemical-protein relations with ensembles of SVM and deep learning models.

Yifan Peng, Anthony Rios, Ramakanth Kavuluru, Zhiyong Lu

Abstract read
In one paragraph

Article in Database : the journal of biological databases and curation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. LitTx: A New Treatment Relation Extraction Dataset.LREC ... International Conference on Language Resources & Evaluation : [proceedings]. International Conference on Language Resources & Evaluation · 2026
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  3. Review
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  7. Prompt Tuning in Biomedical Relation Extraction.Journal of healthcare informatics research · 2024
    Article
  8. Article
  9. Article
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  13. End-to-EndProceedings. IEEE International Conference on Healthcare Informatics · 2023
    Article
  14. Article
  15. Article
  16. A sequence labeling framework for extracting drug-protein relations from biomedical literature.Database : the journal of biological databases and curation · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. The risk of racial bias while tracking influenza-related content on social media using machine learning.Journal of the American Medical Informatics Association : JAMIA · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yifan PengNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.
Anthony RiosNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.
Ramakanth KavuluruDepartment of Computer Science, University of Kentucky, Lexington, KY, USA.
Zhiyong LuNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.

Funding

Named Entity Recognition and Relationship Extraction in BiomedicineZIALM091813 · NLM · NATIONAL LIBRARY OF MEDICINE · PI LU, ZHIYONG · 2013 to 2022
$13.4M
From Syntactic Relations to Semantic Predications: Porting Open Information Extraction to BiomedicineR21LM012274 · NLM · UNIVERSITY OF KENTUCKY · PI KAVULURU, VENKATA NAGA RAMAKANTH · 2016 to 2017
$374k
NLM NIH HHS R21 LM012274
6 · The paper itself

Abstract

Mining relations between chemicals and proteins from the biomedical literature is an increasingly important task. The CHEMPROT track at BioCreative VI aims to promote the development and evaluation of systems that can automatically detect the chemical-protein relations in running text (PubMed abstracts). This work describes our CHEMPROT track entry, which is an ensemble of three systems, including a support vector machine, a convolutional neural network, and a recurrent neural network. Their output is combined using majority voting or stacking for final predictions. Our CHEMPROT system obtained 0.7266 in precision and 0.5735 in recall for an F-score of 0.6410 during the challenge, demonstrating the effectiveness of machine learning-based approaches for automatic relation extraction from biomedical literature and achieving the highest performance in the task during the 2017 challenge.Database URL: http://www.biocreative.org/tasks/biocreative-vi/track-5/.

Indexed as

Databases, ChemicalMachine LearningModels, TheoreticalSupport Vector MachineDatabases, ProteinData CurationNeural Networks, ComputerProteinsReproducibility of ResultsProteins

Identifiers

PMID30020437
PMCPMC6051439

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.