Evidence map›Paper›PMID 30019954›Full record

ReviewExpert review of medical devices2018

Optimal site selection and image fusion guidance technology to facilitate cardiac resynchronization therapy.

Benjamin J Sieniewicz, Justin Gould, Bradley Porter, Baldeep S Sidhu, Jonathan M Behar, Simon Claridge, Steve Niederer, Christopher A Rinaldi

Open access · hybridAbstract readReview
In one paragraph

Review in Expert review of medical devices, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  9. Leadless left ventricular endocardial pacing for CRT upgrades in previously failed and high-risk patients in comparison with coronary sinus CRT upgrades.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Benjamin J Sieniewicza Division of Imaging Sciences and Biomedical Engineering , King's College London , London , United Kingdom.
Justin Goulda Division of Imaging Sciences and Biomedical Engineering , King's College London , London , United Kingdom.
Bradley Portera Division of Imaging Sciences and Biomedical Engineering , King's College London , London , United Kingdom.
Baldeep S Sidhua Division of Imaging Sciences and Biomedical Engineering , King's College London , London , United Kingdom.
Jonathan M Behara Division of Imaging Sciences and Biomedical Engineering , King's College London , London , United Kingdom.
Simon Claridgea Division of Imaging Sciences and Biomedical Engineering , King's College London , London , United Kingdom.
Steve Niederera Division of Imaging Sciences and Biomedical Engineering , King's College London , London , United Kingdom.
Christopher A Rinaldia Division of Imaging Sciences and Biomedical Engineering , King's College London , London , United Kingdom.
King's College London · GBGuy's and St Thomas' NHS Foundation Trust · GB

Funding

British Heart Foundation PG/16/108/32593Department of Health II-LB-1116-20001
6 · The paper itself

Abstract

introductionCardiac resynchronization therapy (CRT) has emerged as one of the few effective treatments for heart failure. However, up to 50% of patients derive no benefit. Suboptimal left ventricle (LV) lead position is a potential cause of poor outcomes while targeted lead deployment has been associated with enhanced response rates. Image-fusion guidance systems represent a novel approach to CRT delivery, allowing physicians to both accurately track and target a specific location during LV lead deployment. AREAS COVERED: This review will provide a comprehensive evaluation of how to define the optimal pacing site. We will evaluate the evidence for delivering targeted LV stimulation at sites displaying favorable viability or advantageous mechanical or electrical properties. Finally, we will evaluate several emerging image-fusion guidance systems which aim to facilitate optimal site selection during CRT. EXPERT COMMENTARY: Targeted LV lead deployment is associated with reductions in morbidity and mortality. Assessment of tissue characterization and electrical latency are critical and can be achieved in a number of ways. Ultimately, the constraints of coronary sinus anatomy have forced the exploration of novel means of delivering CRT including endocardial pacing which hold promise for the future of CRT delivery.

Indexed as

Imaging, Three-DimensionalBiomarkersCardiac Resynchronization TherapyEndocardiumHeart VentriclesHumansTreatment OutcomeBiomarkersCRTelectrical latencyheart failureimage fusionimage guidancemechanical latencysite selectiontissue viability

Identifiers

PMID30019954
PMCPMC6178093
OpenAlexW2882991413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.