ArticleAmerican journal of physiology. Renal physiology2018
Endocrine disruptor bisphenol A is implicated in urinary voiding dysfunction in male mice.
Article in American journal of physiology. Renal physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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Who cites it
18 citing papers in PubMed, 27 citations in OpenAlex.
- PCB Exposure in Adult Male Mice Reduces Proliferating Cells in the Prostate but Minimally Alters Voiding.Toxics · 2026Article
- The assumption of a threshold is false in risk assessments for endocrine disrupting chemicals (EDCs) when endogenous hormones being disrupted are already above any possible threshold: a policy failure by the US FDA.Environmental health : a global access science source · 2026Review
- Protective role of astaxanthin against bisphenol A induced biochemical and histopathological alterations in rat kidneys.Iranian journal of basic medical sciences · 2025Article
- Developmental polychlorinated biphenyl (PCB) exposure impacts on voiding physiology persist into adulthood and influence sensitivity to bladder stimuli in mice.Current research in toxicology · 2025Article
- The Conflict between Regulatory Agencies over the 20,000-Fold Lowering of the Tolerable Daily Intake (TDI) for Bisphenol A (BPA) by the European Food Safety Authority (EFSA).Environmental health perspectives · 2024Article
- The Relationship between Typical Environmental Endocrine Disruptors and Kidney Disease.Toxics · 2022Review
- Natural Products in Mitigation of Bisphenol A Toxicity: Future Therapeutic Use.Molecules (Basel, Switzerland) · 2022Review
- Bisphenol-A analogs induce lower urinary tract dysfunction in male mice.Biochemical pharmacology · 2022Article
- Male Lower Urinary Tract Dysfunction: An Underrepresented Endpoint in Toxicology Research.Toxics · 2022Review
- Bisphenol A affects vipergic nervous structures in the porcine urinary bladder trigone.Scientific reports · 2021Article
- Update on the Health Effects of Bisphenol A: Overwhelming Evidence of Harm.Endocrinology · 2021Review
- Genetic background but not prostatic epithelial beta-catenin influences susceptibility of male mice to testosterone and estradiol-induced urinary dysfunction.American journal of clinical and experimental urology · 2021Article
- In utero and lactational PCB exposure drives anatomic changes in the juvenile mouse bladder.Current research in toxicology · 2021Article
- Data integration, analysis, and interpretation of eight academic CLARITY-BPA studies.Reproductive toxicology (Elmsford, N.Y.) · 2020Article
- Review
- Interactive Effects of Perinatal BPA or DES and Adult Testosterone and Estradiol Exposure on Adult Urethral Obstruction and Bladder, Kidney, and Prostate Pathology in Male Mice.International journal of molecular sciences · 2020Article
- High-definition ultrasound characterization of acute cyclophosphamide-induced cystitis in the mouse.Investigative and clinical urology · 2020Article
- Fetal bisphenol A and ethinylestradiol exposure alters male rat urogenital tract morphology at birth: Confirmation of prior low-dose findings in CLARITY-BPA.Reproductive toxicology (Elmsford, N.Y.) · 2020Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
Abstract
Estrogens, acting synergistically with androgens, are known from animal experiments to be important in lower urinary tract symptoms (LUTS) and benign prostate enlargement. Human exposure to environmental estrogens occurs throughout the life span, but the urologic health risks in men are largely unknown. Bisphenol A (BPA) is an endocrine disruptor implicated in male urogenital malformations. Given the role of estrogens in male LUTS, we studied the effects of BPA administered in combination with testosterone (T) on the urinary voiding behavior of adult male mice. Adult male mice underwent subcutaneous implantation with slow-release pellets of 25 mg BPA or 2.5 mg estradiol-17β (E
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.