ArticleSurgical endoscopy2019
Laparoscopic pyloroplasty versus endoscopic per-oral pyloromyotomy for the treatment of gastroparesis.
Article in Surgical endoscopy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 3 syntheses or guidelines pooled it, 95 citations in OpenAlex.
- Pooled it
- Gastric per-Oral Endoscopic Myotomy for Refractory Gastroparesis: A Meta-Analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021Pooled it
- Pooled it
- Efficacy of gastric per oral endoscopic myotomy for gastroparesis symptoms.Surgical endoscopy · 2026Article
- Clinical insights into diabetic gastroparesis: gastric scintigraphy-based diagnosis and treatment outcomes.BMC gastroenterology · 2025Article
- Pyloric drainage interventions for gastroparesis: a comparison of laparoscopic pyloroplasty and gastric peroral endoscopic myotomy (G-POEM) outcomes.Surgical endoscopy · 2025Article
- Pyloric Dysfunction: A Review of the Mechanisms, Diagnosis, and Treatment.Gut and liver · 2025Review
- Outcomes after per oral pyloromyotomy based on gastroparesis etiology.Surgical endoscopy · 2025Article
- A long-term follow-up study of gastric peroral endoscopic myotomy (G-POEM) in a large cohort of patients with postsurgical gastroparesis.Surgical endoscopy · 2024Article
- Applications of gastric peroral endoscopic myotomy in the treatment of upper gastrointestinal tract disease.World journal of gastrointestinal surgery · 2024Review
- Article
- Precision Endoscopy in Peroral Myotomies for Motility Disorders of the Upper Gastrointestinal Tract: Current Insights and Prospective Avenues-A Comprehensive Review.Life (Basel, Switzerland) · 2023Review
- Long-term outcomes (≥3 years) after gastric peroral endoscopic myotomy for refractory gastroparesis: a systematic review and meta-analysis.iGIE : innovation, investigation and insights · 2023Article
- Predictors of favorable outcome after pyloroplasty for gastroparesis: should response to pyloric dilation or Botox injection be used as a marker of surgical outcome?Surgical endoscopy · 2023Article
- Review
- Gastric peroral endoscopic myotomy versus surgical pyloromyotomy/pyloroplasty for refractory gastroparesis: systematic review and meta-analysis.Endoscopy international open · 2023Article
- [S156] Comparing outcomes of per-oral pyloromyotomy and robotic pyloroplasty for the treatment of gastroparesis.Surgical endoscopy · 2023Article
- Endoscopic findings do not predict per-oral pyloromyotomy (POP) response.Surgical endoscopy · 2023Article
- Targeting the pylorus in gastroparesis: From physiology to endoscopic pyloromyotomy.Neurogastroenterology and motility · 2023Review
- Gastric peroral endoscopic pyloromyotomy (G-POEM) in patients with refractory gastroparesis: a review.Therapeutic advances in gastroenterology · 2023Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGastroparesis is a debilitating functional disorder of the stomach characterized by delayed gastric emptying absent an obstructive etiology. Surgical or endoscopic disruption of the pylorus has been utilized to treat this disease, but there is little evidence comparing laparoscopic pyloroplasty (LP) with endoscopic per-oral pyloromyotomy (POP). Herein we describe our experience at our institution using a propensity-matched cohort study to compare outcomes between these procedures.
methodsAll patients who underwent LP for the treatment of gastroparesis from October 2014 through September 2017 at our institution were retrospectively reviewed. Propensity scoring was used to match these patients 1:1 to patients undergoing POP during this time period based on gender, age, and etiology of gastroparesis. Symptom scores using the Gastroparesis Cardinal Symptom Index (GCSI), scintigraphic gastric emptying studies (GES), and perioperative outcomes were compared between matched cohorts. Thirty patients underwent LP for gastroparesis during the study period which were matched 1:1 with patients undergoing POP. The etiology of gastroparesis was 63.3% idiopathic (n = 19), 20.0% post-surgical (n = 6), and 16.7% diabetic (n = 5) in both cohorts.
resultsPatients who underwent LP had a longer average length of stay (4.6 vs. 1.4 days, p = 0.003), operative time (99.3 vs. 33.9 min, p < 0.001), and estimated blood loss (12.9 vs. 0.4 mL, p < 0.001). There were more complications in the LP cohort (16.7 vs. 3.3%, p = 0.086), which included surgical site infection (6.7 vs. 0%, p = 0.153), pneumonia (6.7 vs. 0.0%, p = 0.153), and unplanned ICU admission (10.0 vs. 0.0%, p = 0.078). LP and POP both resulted in similar, significant improvements in both in GCSI scores and objective gastric emptying.
conclusionsPer-oral endoscopic pyloromyotomy (POP) is safe and effective for the treatment of medical refractory gastroparesis. POP has less perioperative morbidity compared to LP with comparative functional outcomes.
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