Evidence map›Paper›PMID 30019215›Full record

ArticleCellular and molecular life sciences : CMLS2018

eIF2A, an initiator tRNA carrier refractory to eIF2α kinases, functions synergistically with eIF5B.

Eunah Kim, Joon Hyun Kim, Keunhee Seo, Ka Young Hong, Seon Woo A An, Junyoung Kwon, Seung-Jae V Lee, Sung Key Jang

Open access · hybridAbstract read
In one paragraph

Article in Cellular and molecular life sciences : CMLS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
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  8. Article
  9. Review
  10. Article
  11. Heme-regulated inhibitor: an overlooked eIF2α kinase in cancer investigations.Medical oncology (Northwood, London, England) · 2022
    Review
  12. Unconventional translation initiation factor EIF2A is required for Drosophila spermatogenesis.Developmental dynamics : an official publication of the American Association of Anatomists · 2022
    Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Hepatitis C Virus Translation Regulation.International journal of molecular sciences · 2020
    Review
  20. A Retrospective on eIF2A-and Not the Alpha Subunit of eIF2.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Eunah KimPBC, Department of Life Sciences, Pohang University of Science and Technology, Cheongam-ro 77, Nam-gu, Pohang-si, Gyeongsangbuk-do, 37673, Republic of Korea.
Joon Hyun KimPBC, Department of Life Sciences, Pohang University of Science and Technology, Cheongam-ro 77, Nam-gu, Pohang-si, Gyeongsangbuk-do, 37673, Republic of Korea.
Keunhee SeoPBC, Department of Life Sciences, Pohang University of Science and Technology, Cheongam-ro 77, Nam-gu, Pohang-si, Gyeongsangbuk-do, 37673, Republic of Korea.
Ka Young HongPBC, Department of Life Sciences, Pohang University of Science and Technology, Cheongam-ro 77, Nam-gu, Pohang-si, Gyeongsangbuk-do, 37673, Republic of Korea.
Seon Woo A AnPBC, Department of Life Sciences, Pohang University of Science and Technology, Cheongam-ro 77, Nam-gu, Pohang-si, Gyeongsangbuk-do, 37673, Republic of Korea.
Junyoung KwonPBC, Department of Life Sciences, Pohang University of Science and Technology, Cheongam-ro 77, Nam-gu, Pohang-si, Gyeongsangbuk-do, 37673, Republic of Korea.
Seung-Jae V LeePBC, Department of Life Sciences, Pohang University of Science and Technology, Cheongam-ro 77, Nam-gu, Pohang-si, Gyeongsangbuk-do, 37673, Republic of Korea.
Sung Key JangPBC, Department of Life Sciences, Pohang University of Science and Technology, Cheongam-ro 77, Nam-gu, Pohang-si, Gyeongsangbuk-do, 37673, Republic of Korea. sungkey@postech.ac.kr.
Pohang University of Science and Technology · KR

Funding

National Research Foundation of Korea 2017R1A2B3009902National Research Foundation of Korea 2017R1A5A1015366
6 · The paper itself

Abstract

The initiator tRNA (Met-tRNA

Indexed as

Amino Acid SequenceAnimalsBlotting, WesternCaenorhabditis elegansCaenorhabditis elegans ProteinseIF-2 KinaseEukaryotic Initiation Factor-2Eukaryotic Initiation FactorsHEK293 CellsHumansMutationProtein BindingRNA InterferenceRNA, Transfer, MetSequence Homology, Amino AcidCaenorhabditis elegans ProteinseIF-2 KinaseEukaryotic Initiation Factor-2eukaryotic initiation factor-5BEukaryotic Initiation FactorsRNA, Transfer, MeteIF2AeIF5BEvolution of initiator tRNA carriersTranslation initiation

Identifiers

PMID30019215
PMCPMC6208778
OpenAlexW2883153215

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.