Evidence map›Paper›PMID 30019153›Full record

ArticleMolecular biology reports2018

CXCL13 polymorphism is associated with essential hypertension in Tatars from Russia.

Yanina R Timasheva, Timur R Nasibullin, Ilsiyar A Tuktarova, Vera V Erdman, Olga E Mustafina

Abstract read
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In one paragraph

Article in Molecular biology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yanina R TimashevaLaboratory of Physiological Genetics, Institute of Biochemistry and Genetics of Ufa Federal Research Centre of Russian Academy of Sciences, October Avenue 71, Ufa, Russian Federation, 450054. ianina_t@mail.ru.ORCID http://orcid.org/0000-0002-9918-6962
Timur R NasibullinLaboratory of Physiological Genetics, Institute of Biochemistry and Genetics of Ufa Federal Research Centre of Russian Academy of Sciences, October Avenue 71, Ufa, Russian Federation, 450054.ORCID http://orcid.org/0000-0001-8823-8678
Ilsiyar A TuktarovaLaboratory of Physiological Genetics, Institute of Biochemistry and Genetics of Ufa Federal Research Centre of Russian Academy of Sciences, October Avenue 71, Ufa, Russian Federation, 450054.
Vera V ErdmanLaboratory of Physiological Genetics, Institute of Biochemistry and Genetics of Ufa Federal Research Centre of Russian Academy of Sciences, October Avenue 71, Ufa, Russian Federation, 450054.ORCID http://orcid.org/0000-0002-1219-3458
Olga E MustafinaLaboratory of Physiological Genetics, Institute of Biochemistry and Genetics of Ufa Federal Research Centre of Russian Academy of Sciences, October Avenue 71, Ufa, Russian Federation, 450054.ORCID http://orcid.org/0000-0002-5118-6533
Ufa Institute of Chemistry · RUBashkir State University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Essential arterial hypertension is a disease with distinct yet unexplored inflammatory component. Our aim was to assess the role of chemokine genes and their interaction in its development. Genotyping of polymorphic markers in six chemokine genes (CXCL13, CCL8, CCL16, CCL17, CCL18, and CCL23) was performed in the group of 522 men of Tatar ethnic origin from the Republic of Bashkortostan, Russia (213 patients with essential hypertension and 309 healthy individuals without history of cardiovascular disease). We found a strong association of CXCL13 rs355689*C allele with essential hypertension under additive (OR 0.56, P

Indexed as

AdultAllelesChemokine CXCL13ChemokinesEssential HypertensionEthnicityGene FrequencyGenetic Predisposition to DiseaseGenotypeHumansHypertensionMaleMiddle AgedPolymorphism, GeneticRussiaChemokine CXCL13ChemokinesCXCL13 protein, humanChemokinesEssential hypertensionGenetic testingRisk prediction

Identifiers

PMID30019153
OpenAlexW2884202937

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.