Evidence map›Paper›PMID 30019029›Full record

ArticleCurrent developments in nutrition2018

Dietary Bovine Lactoferrin Reduces

Elizabeth A Reznikov, Sarah S Comstock, Jennifer L Hoeflinger, Mei Wang, Michael J Miller, Sharon M Donovan

Open access · goldAbstract read
In one paragraph

Article in Current developments in nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

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  9. [A review on the relationship between breast milk nutrients and brain development in preterm infants].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Elizabeth A ReznikovDivision of Nutritional Sciences.
Sarah S ComstockDepartment of Food Science and Human Nutrition, Michigan State University, East Lansing, MI.
Jennifer L HoeflingerDepartment of Food Science and Human Nutrition, University of Illinois, Urbana, IL.
Mei WangDepartment of Food Science and Human Nutrition, University of Illinois, Urbana, IL.
Michael J MillerDivision of Nutritional Sciences.
Sharon M DonovanDivision of Nutritional Sciences.
University of Illinois Urbana-Champaign · USMichigan State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBovine lactoferrin (bLf) reduces

objectiveThe aim was to determine the effects of oral administration of bLf and

methodsColostrum-deprived piglets were fed formulas containing 4 g whey/L (CON group) or bLf (LF group). One-half of the piglets in each group were gavaged with

resultsPreinfection, LF piglets had lower serum interleukin 10 (IL-10), a higher percentage of lymphocytes, and a lower percentage of neutrophils than BI or COMB piglets. After infection, dietary bLf increased piglet weight gain, reduced staphylococcal counts in the kidneys, and tended to lower staphylococcal counts in the lungs and heart. Dietary bLf also decreased kidney IL-10 and increased lung interferon γ (IFN-γ) mRNA.

conclusionsDietary bLf and

Indexed as

immune systeminfectionlactoferrinneonateprobioticsepsisStaphylococcus aureus

Identifiers

PMID30019029
PMCPMC6041752
OpenAlexW2781361244

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.