Evidence map›Paper›PMID 30018946›Full record

ReviewCanadian journal of gastroenterology & hepatology2018

The Molecular Basis and Therapeutic Potential of

Rei Mizuno, Kenji Kawada, Yoshiharu Sakai

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Canadian journal of gastroenterology & hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Dysregulated miRNAs Targeting Adiponectin Signaling in Colorectal Cancer.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rei MizunoDepartment of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kenji KawadaDepartment of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID 0000-0003-4336-6937
Yoshiharu SakaiDepartment of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although a number of studies have revealed the underlying mechanisms which regulate the development of colorectal cancer (CRC), we have not completely overcome this disease yet. Accumulating evidence has shown that the posttranscriptional regulation by the noncoding RNAs such as microRNAs plays an important role in the development or progression of CRC. Among a number of microRNAs, the

Indexed as

ApoptosisCell CycleCell ProliferationColonic NeoplasmsDisease ProgressionDrug Resistance, NeoplasmGenetic TherapyHumansMicroRNAsRNA-Binding ProteinsLIN28B protein, humanMicroRNAsmirnlet7 microRNA, humanRNA-Binding Proteins

Identifiers

PMID30018946
PMCPMC6029494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.