Evidence map›Paper›PMID 30018830›Full record

ArticleCase reports in hematology2018

Acquired Factor VIII Inhibitor Presenting as Occult GI Bleeding.

Carlos I Pacheco Cano, Marilyn A Arosemena, Roumen B Iordanov, Ankitha Lingamaneni, Ankur Aneja

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in hematology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Carlos I Pacheco CanoDepartment of Medicine, Jackson Memorial Hospital, University of Miami, Miami, FL, USA.ORCID 0000-0003-1439-0639
Marilyn A ArosemenaDepartment of Medicine, Jackson Memorial Hospital, University of Miami, Miami, FL, USA.ORCID 0000-0002-8185-4707
Roumen B IordanovDepartment of Medicine, Jackson Memorial Hospital, University of Miami, Miami, FL, USA.ORCID 0000-0002-7554-4737
Ankitha LingamaneniUniversity of Miami Miller School of Medicine, Miami, FL, USA.
Ankur AnejaUniversity of Miami Miller School of Medicine, Miami, FL, USA.
University of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An acquired coagulation factor deficiency is characterized by acquired autoantibodies against specific clotting factors in those without diagnosed hemophilia. It is a relatively rare condition with an incidence of approximately one case per million per year. We present a case report of an elderly male who initially presented with an occult GI bleed that was identified with a positive fecal occult blood test result. This is the first case reported to our knowledge of an acquired factor inhibitor deficiency presenting in this manner. We postulate the importance of acquired factor inhibitors in the setting of unexplained anemia given absence of overt clinical symptoms that could contribute to aggravate an established GI bleed, especially in the elderly population.

Identifiers

PMID30018830
PMCPMC6029490
OpenAlexW2809365855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.