Evidence map›Paper›PMID 30018755›Full record

ArticleJournal of healthcare engineering2018

Comparison of Machine-Learning Classification Models for Glaucoma Management.

Guangzhou An, Kazuko Omodaka, Satoru Tsuda, Yukihiro Shiga, Naoko Takada, Tsutomu Kikawa, Toru Nakazawa, Hideo Yokota, Masahiro Akiba

Abstract readComparative Study
In one paragraph

Article in Journal of healthcare engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. The march to harmonized imaging standards for retinal imaging.Progress in retinal and eye research · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Development of the Integrated Glaucoma Risk Index.Diagnostics (Basel, Switzerland) · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Big data in visual field testing for glaucoma.Taiwan journal of ophthalmology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Guangzhou AnR&D Division, Topcon Corporation, Tokyo, Japan.ORCID 0000-0002-0875-4494
Kazuko OmodakaTohoku University Graduate School of Medicine, Sendai, Japan.
Satoru TsudaTohoku University Graduate School of Medicine, Sendai, Japan.
Yukihiro ShigaTohoku University Graduate School of Medicine, Sendai, Japan.ORCID 0000-0001-5531-7409
Naoko TakadaTohoku University Graduate School of Medicine, Sendai, Japan.
Tsutomu KikawaR&D Division, Topcon Corporation, Tokyo, Japan.
Toru NakazawaTohoku University Graduate School of Medicine, Sendai, Japan.
Hideo YokotaR&D Division, Topcon Corporation, Tokyo, Japan.
Masahiro AkibaR&D Division, Topcon Corporation, Tokyo, Japan.ORCID 0000-0002-2735-5763

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study develops an objective machine-learning classification model for classifying glaucomatous optic discs and reveals the classificatory criteria to assist in clinical glaucoma management. In this study, 163 glaucoma eyes were labelled with four optic disc types by three glaucoma specialists and then randomly separated into training and test data. All the images of these eyes were captured using optical coherence tomography and laser speckle flowgraphy to quantify the ocular structure and blood-flow-related parameters. A total of 91 parameters were extracted from each eye along with the patients' background information. Machine-learning classifiers, including the neural network (NN), naïve Bayes (NB), support vector machine (SVM), and gradient boosted decision trees (GBDT), were trained to build the classification models, and a hybrid feature selection method that combines minimum redundancy maximum relevance and genetic-algorithm-based feature selection was applied to find the most valid and relevant features for NN, NB, and SVM. A comparison of the performance of the three machine-learning classification models showed that the NN had the best classification performance with a validated accuracy of 87.8% using only nine ocular parameters. These selected quantified parameters enabled the trained NN to classify glaucomatous optic discs with relatively high performance without requiring color fundus images.

Indexed as

Machine LearningAlgorithmsBayes TheoremDecision TreesEyeGlaucomaHumansNerve NetOptic DiskRegional Blood FlowTomography, Optical Coherence

Identifiers

PMID30018755
PMCPMC6029465

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.