Evidence map›Paper›PMID 30018701›Full record

ReviewAmerican journal of translational research2018

The progress of circular RNAs in various tumors.

Dandan Wang, Sujin Yang, Hui Wang, Jinyan Wang, Qian Zhang, Siying Zhou, Yunjie He, Heda Zhang, Fei Deng, Hanzi Xu and 3 more

Abstract readReview
In one paragraph

Review in American journal of translational research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  5. Article
  6. The NMolecular cancer · 2022
    Article
  7. Review
  8. Article
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  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Observational
  16. Article
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  19. CircNFIX promotes progression of glioma through regulating miR-378e/RPN2 axis.Journal of experimental & clinical cancer research : CR · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Dandan WangDepartment of General Surgery, The First Affiliated Hospital with Nanjing Medical University Nanjing 210029, China.
Sujin YangDepartment of General Surgery, The First Affiliated Hospital with Nanjing Medical University Nanjing 210029, China.
Hui WangJiangsu Jiankang Vocational College Nanjing 210000, China.
Jinyan WangDepartment of General Surgery, The First Affiliated Hospital with Nanjing Medical University Nanjing 210029, China.
Qian ZhangDepartment of General Surgery, The First Affiliated Hospital with Nanjing Medical University Nanjing 210029, China.
Siying ZhouThe First Clinical Medical College, Nanjing University of Traditional Chinese Medicine Nanjing 210023, China.
Yunjie HeDepartment of General Surgery, The First Affiliated Hospital with Nanjing Medical University Nanjing 210029, China.
Heda ZhangDepartment of General Surgery, Southeast University Medical School Nanjing 210009, China.
Fei DengDepartment of General Surgery, The First Affiliated Hospital with Nanjing Medical University Nanjing 210029, China.
Hanzi XuDepartment of Radiation Oncology, Jiangsu Cancer Hospital Affiliated to Nanjing Medical University Nanjing 210009, China.
Shanliang ZhongCenter of Clinical Laboratory Science, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research and The Affiliated Cancer Hospital of Nanjing Medical University Nanjing 210009, China.
Li FuDepartment of Breast Cancer Pathology and Research Laboratory, Key Laboratory of Breast Cancer Prevention and Therapy, National Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital Tianjin, China.
Jinhai TangDepartment of General Surgery, The First Affiliated Hospital with Nanjing Medical University Nanjing 210029, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circular RNAs (circRNAs), a novel type of non-coding RNAs, presented as covalently closed continuous loops. Recent researches had found that circRNAs could function as microRNA sponges, regulators of gene transcription and encoding proteins. They were relatively stable and expressed widely in cytoplasm, which played important roles in carcinogenesis of cancers, such as esophageal cancer, gastric cancer, colorectal cancer, hepatocarcinoma, bladder cancer, glioma, breast cancer, osteosarcoma and so on. Furthermore, they were involved in many biological functions, like cell proliferation, drug resistance, cell cycle, invasion and metastasis. Therefore, the further studies were meaningful on the mechanism of cancers and circRNAs. In the review, we will summarize the current biogenesis of circRNAs and the roles of them in various cancers, which might be a novel biomarker and therapeutic avenue.

Indexed as

biomarkercancerscircRNAstherapeutic targets

Identifiers

PMID30018701
PMCPMC6038087

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.