Evidence map›Paper›PMID 30018381›Full record

ArticleNature communications2018

Dynamic and programmable morphology and size evolution via a living hierarchical self-assembly strategy.

Xing Wang, Peiyuan Gao, Yanyu Yang, Hongxia Guo, Decheng Wu

Abstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Rigid Supramolecular Aramid Nanotubes as Catalyst Supports.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Mechanically Robust Hydrogels Facilitating Bone Regeneration through Epigenetic Modulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Frontiers in bioengineering and biotechnology · 2021
    Article
  14. Advances of Hydrogel-Based Bioprinting for Cartilage Tissue Engineering.Frontiers in bioengineering and biotechnology · 2021
    Review
  15. Article
  16. Review
  17. Current Trends of Targeted Drug Delivery for Oral Cancer Therapy.Frontiers in bioengineering and biotechnology · 2020
    Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xing WangBeijing National Laboratory for Molecular Sciences, State Key Laboratory of Polymer Physics & Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.
Peiyuan GaoPacific Northwest National Laboratory, Richland, 99352, WA, USA.
Yanyu YangBeijing National Laboratory for Molecular Sciences, State Key Laboratory of Polymer Physics & Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.
Hongxia GuoBeijing National Laboratory for Molecular Sciences, State Key Laboratory of Polymer Physics & Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.
Decheng WuBeijing National Laboratory for Molecular Sciences, State Key Laboratory of Polymer Physics & Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China. dcwu@iccas.ac.cn.

Funding

National Natural Science Foundation of China (National Science Foundation of China) 21474115National Natural Science Foundation of China (National Science Foundation of China) 21504096National Natural Science Foundation of China (National Science Foundation of China) 21674120National Natural Science Foundation of China (National Science Foundation of China) 21725403
6 · The paper itself

Abstract

Recent advances in the preparation of shape-shifting and size-growing nanostructures are hot topics in development of nanoscience, because many intelligent functions are always relied on their shape and dimension. Here we report a tunable manipulation of sequential self-assembled transformation in situ via a hierarchical assembly strategy based on a living thiol-disulfide exchange reaction. By tailoring the external stimuli, the reactive points can be generated at the ends of initially unimolecular micelles, which subsequently drive the pre-assemblies to periodically proceed into the hierarchically micellar connection, axial growth, bending, and cyclization processes from nanoscopic assemblies to macroscopic particles. Of particular interest would be systems that acquired the shape control and size adjustment of self-assemblies after termination or reactivation of disulfide reshuffling reaction by regulating external stimuli whenever needed. Such a hierarchical strategy for self-assembled evolution is universally applicable not only for other disulfide-linked dendritic polymers but also for exploitation of biological applications.

Indexed as

CyclizationDendrimersDisulfidesHumansHydrogen-Ion ConcentrationMicellesMolecular Dynamics SimulationNanostructuresNanotechnologyPolyethylene GlycolsSulfhydryl CompoundsDendrimersDisulfidesMicellesPolyethylene GlycolsSulfhydryl Compounds

Identifiers

PMID30018381
PMCPMC6050331

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.