ArticleMolecules (Basel, Switzerland)2018
Anti-glycation, Carbonyl Trapping and Anti-inflammatory Activities of Chrysin Derivatives.
Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Preclinical evidence of chrysin in metabolic disorder via mitochondrial signaling: a mechanistic review.Molecular biology reports · 2026Review
- Structural Speciation of Hybrid Ti(IV)-Chrysin Systems-Biological Profiling and Antibacterial, Anti-Inflammatory, and Tissue-Specific Anticancer Activity.Molecules (Basel, Switzerland) · 2025Article
- Review
- Generation and Accumulation of Various Advanced Glycation End-Products in Cardiomyocytes May Induce Cardiovascular Disease.International journal of molecular sciences · 2024Review
- Article
- Exploring the Interplay between Polyphenols and Lysyl Oxidase Enzymes for Maintaining Extracellular Matrix Homeostasis.International journal of molecular sciences · 2023Review
- Highly water-soluble diacetyl chrysin ameliorates diabetes-associated renal fibrosis and retinal microvascular abnormality in db/db mice.Nutrition research and practice · 2023Article
- A Relook into the Flavonoid Chemical Space ofJournal of analytical methods in chemistry · 2023Article
- Major anthocyanins in elderberry effectively trap methylglyoxal and reduce cytotoxicity of methylglyoxal in HepG2 cell line.Food chemistry: X · 2022Article
- Design, synthesis, in vitro, in silico, and SAR studies of flavone analogs towards anti-dengue activity.Scientific reports · 2022Article
- Ursolic acid and its isomer oleanolic acid are responsible for the anti-dementia effects of Ocimum sanctum in olfactory bulbectomized mice.Journal of natural medicines · 2022Article
- Inhibitory effect of LSOPC on AGEs formation and sensory quality in cookies.Frontiers in nutrition · 2022Article
- Protective effects of 7-hydroxyethyl chrysin on rats with exercise-induced fatigue in hypobaric hypoxia environment.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2021Article
- Effect of the natural flavonoids myricetin and dihydromyricetin on the wound healing process in vitro.Journal of applied biomedicine · 2021Article
- Investigation of the Phytochemical Composition, Antioxidant Activity, and Methylglyoxal Trapping Effect ofMolecules (Basel, Switzerland) · 2020Article
- Screening and Characterization of Antiglycoxidant Anthocyanins fromAntioxidants (Basel, Switzerland) · 2020Article
- Mechanisms of honey on testosterone levels.Heliyon · 2019Review
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was searching anti-glycation, carbonyl trapping and anti-inflammatory activities of chrysin derivatives. The inhibitory effect of chrysin on advanced glycation end-products (AGEs) was investigated by trapping methylglyoxal (MGO), and MGO-conjugated adducts of chrysin were analyzed using LC-MS/MS. The mono- or di-MGO-conjugated adducts of chrysin were present at 63.86 and 29.69% upon 48 h of incubation at a chrysin:MGO ratio of 1:10. The MGO adducted positions on chrysin were at carbon 6 or 6 & 8 in the A ring by classic aldol condensation. To provide applicable knowledge for developing chrysin derivatives as AGE inhibitors, we synthesized several
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