Article in The Plant cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
8 citing papers in PubMed, 19 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
29 authors at 10 institutions in 6 countries.
Kiril MishevDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.ORCID 0000-0001-5849-8786
Qing LuDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.ORCID 0000-0002-4703-3286
Bram DenooDepartment of Organic and Macromolecular Chemistry, Ghent University, 9000 Ghent, Belgium.
François PeuroisLaboratoire de Biologie et Pharmacologie Appliquée, Centre National de la Recherche Scientifique, Ecole Normale Supérieure Paris-Saclay, 94235 Cachan, France.ORCID 0000-0003-1216-1162
Wim DejongheDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.ORCID 0000-0003-3869-2228
Jan HullaertDepartment of Organic and Macromolecular Chemistry, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-7860-378X
Riet De RyckeDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.ORCID 0000-0001-8270-7015
Sjef BoerenLaboratory of Biochemistry, Wageningen University, 6708 Wageningen, The Netherlands.ORCID 0000-0002-0847-8821
Marine BretouLaboratory for Membrane Trafficking, VIB Center for Brain and Disease Research, KU Leuven, Department of Neurosciences, 3000 Leuven, Belgium.
Steven De MunckLaboratory for Protein Biochemistry and Biomolecular Engineering, Department of Biochemistry and Microbiology, Ghent University, 9000 Ghent, Belgium.
Isha SharmaDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.
Kaija GoodmanLaboratory of Cell and Molecular Biology and Departments of Botany and Genetics, University of Wisconsin-Madison, Wisconsin 53706.ORCID 0000-0002-4461-4077
Kamila KalinowskaSchool of Life Sciences Weihenstephan, Technical University of Munich, 85354 Freising, Germany.ORCID 0000-0003-0080-5557
Veronique StormeDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.ORCID 0000-0003-4762-6580
Le Son Long NguyenVIB Screening Core, 9052 Ghent, Belgium.
Sara MartinsInstitute for Integrative Biology of the Cell (I2BC), CNRS/CEA/Université Paris Sud, Université Paris-Saclay, Gif-sur-Yvette 91198, France.ORCID 0000-0003-3910-4168
Wim NerinckxLaboratory for Protein Biochemistry and Biomolecular Engineering, Department of Biochemistry and Microbiology, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-6563-8342
Grégory VertInstitute for Integrative Biology of the Cell (I2BC), CNRS/CEA/Université Paris Sud, Université Paris-Saclay, Gif-sur-Yvette 91198, France.ORCID 0000-0002-0844-9991
Annemieke MadderDepartment of Organic and Macromolecular Chemistry, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0003-0179-7608
Marisa S OteguiLaboratory of Cell and Molecular Biology and Departments of Botany and Genetics, University of Wisconsin-Madison, Wisconsin 53706.ORCID 0000-0003-4699-6950
Erika IsonoSchool of Life Sciences Weihenstephan, Technical University of Munich, 85354 Freising, Germany.
Savvas N SavvidesLaboratory for Protein Biochemistry and Biomolecular Engineering, Department of Biochemistry and Microbiology, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0003-3420-5947
Wim AnnaertLaboratory for Membrane Trafficking, VIB Center for Brain and Disease Research, KU Leuven, Department of Neurosciences, 3000 Leuven, Belgium.
Sacco De VriesLaboratory of Biochemistry, Wageningen University, 6708 Wageningen, The Netherlands.ORCID 0000-0001-9454-775X
Jacqueline CherfilsLaboratoire de Biologie et Pharmacologie Appliquée, Centre National de la Recherche Scientifique, Ecole Normale Supérieure Paris-Saclay, 94235 Cachan, France.
Johan WinneDepartment of Organic and Macromolecular Chemistry, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-9015-4497
Eugenia RussinovaDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium eurus@psb.vib-ugent.be.ORCID 0000-0002-0569-1977
Ghent University · BEUniversity College Ghent · BEÉcole Normale Supérieure Paris-Saclay · FRUniversité Paris-Sud · FRUniversity of Wisconsin System · USVIB-KU Leuven Center for Brain & Disease Research · BEWageningen University & Research · NLBulgarian Academy of Sciences · BGTechnical University of Munich · DEUniversity of Konstanz · DE
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
Small GTP-binding proteins from the ADP-ribosylation factor (ARF) family are important regulators of vesicle formation and cellular trafficking in all eukaryotes. ARF activation is accomplished by a protein family of guanine nucleotide exchange factors (GEFs) that contain a conserved catalytic Sec7 domain. Here, we identified and characterized Secdin, a small-molecule inhibitor of
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Nonselective Chemical Inhibition of Sec7 Domain-Containing ARF GTPase Exchange Factors. · full record | OpenQuestion