Evidence map›Paper›PMID 30018105›Full record

ArticlemBio2018

Phagocytes from Mice Lacking the Sts Phosphatases Have an Enhanced Antifungal Response to Candida albicans.

David Frank, Shamoon Naseem, Gian Luigi Russo, Cindy Li, Kaustubh Parashar, James B Konopka, Nick Carpino

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. TULA Proteins in Men, Mice, Hens, and Lice: Welcome to the Family.International journal of molecular sciences · 2023
    Review
  9. The Sts Proteins: Modulators of Host Immunity.International journal of molecular sciences · 2023
    Review
  10. Review
  11. TULA-Family Regulators of Platelet Activation.International journal of molecular sciences · 2022
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

David FrankProgram in Molecular and Cellular Pharmacology, Stony Brook University, Stony Brook, New York, USA.
Shamoon NaseemDepartment of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York, USA.
Gian Luigi RussoDepartment of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York, USA.
Cindy LiDepartment of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York, USA.
Kaustubh ParasharDepartment of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York, USA.
James B KonopkaDepartment of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York, USA.
Nick CarpinoProgram in Molecular and Cellular Pharmacology, Stony Brook University, Stony Brook, New York, USA nicholas.carpino@stonybrook.edu.ORCID 0000-0002-9231-9160
Stony Brook University · USInstitute of Food Science · IT

Funding

Regulation of Morphogenesis in C. albicansR01AI047837 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI James B Konopka · 2001 to 2026
$8.8M
Establishing a Long Island Bioscience HubU01HL127522 · NHLBI · STATE UNIVERSITY NEW YORK STONY BROOK · PI RUBIN, CLINTON T · 2015 to 2017
$3.0M
Establishing Sts-1 as a novel target for treatment of systemic candidiasisR21AI130859 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI CARPINO, NICHOLAS A · 2018 to 2019
$456k
NHLBI NIH HHS U01 HL127522NIAID NIH HHS R01 AI047837NIAID NIH HHS R21 AI130859
6 · The paper itself

Abstract

Mice lacking expression of the homologous phosphatases Sts-1 and Sts-2 (Sts

Indexed as

AnimalsCandida albicansCandidiasisDectin-1Disease Models, AnimalHost-Pathogen InteractionsLectins, C-TypeMiceMice, KnockoutMonocytesProtein Tyrosine PhosphatasesReactive Oxygen SpeciesReceptors, Antigen, T-CellSignal TransductionSyk KinaseDectin-1Lectins, C-TypeProtein Tyrosine PhosphatasesReactive Oxygen SpeciesReceptors, Antigen, T-CellSts-2 protein, mouseSyk KinaseTULA-2 protein, mouseCandida albicanscell signalingeffector functionshost-pathogen interactionsinnate immunity

Identifiers

PMID30018105
PMCPMC6050958
OpenAlexW2884214035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.