Evidence map›Paper›PMID 30017963›Full record

ArticleThe Journal of urology2018

Painful Bladder Symptoms Related to Somatic Syndromes in a Convenience Sample of Community Women with Overactive Bladder Symptoms.

Casey G Kowalik, Joshua A Cohn, Sophia Delpe, Melissa R Kaufman, Alan Wein, Roger R Dmochowski, W Stuart Reynolds

Open access · greenAbstract read
In one paragraph

Article in The Journal of urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Casey G KowalikDepartment of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee. Electronic address: Casey.kowalik@gmail.com.
Joshua A CohnDepartment of Urology, Einstein Healthcare Network, Philadelphia, Pennsylvania.
Sophia DelpeDepartment of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.
Melissa R KaufmanDepartment of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.
Alan WeinDivision of Urology, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Roger R DmochowskiDepartment of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.
W Stuart ReynoldsDepartment of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.
Vanderbilt University Medical Center · USEinstein Healthcare Network · USUniversity of Pennsylvania · US

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Afferent Hyperactivity Mechanisms in Overactive Bladder SyndromeK23DK103910 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI REYNOLDS, WILLIAM STUART · 2015 to 2019
$737k
NCATS NIH HHS UL1 TR000445NIDDK NIH HHS K23 DK103910
6 · The paper itself

Abstract

purposeWe investigated the relationship of painful bladder filling and urinary urgency to somatic and chronic pain symptoms in women with overactive bladder without an interstitial cystitis/bladder pain syndrome diagnosis. MATERIALS AND

methodsWomen who met overactive bladder criteria based on symptoms were recruited, including 183 (83.9%) from the community and 35 (16.1%) from the urology clinic to complete validated questionnaires assessing urinary symptoms, somatic symptoms and pain syndromes. Participants were categorized into 1 of 3 groups, including 1) neither symptom, 2) either symptom or 3) both symptoms, based on their reports of painful urinary urgency and/or painful bladder filling. Multivariable regression analyses were performed to determine factors predictive of having painful urgency and/or painful filling.

resultsOf 218 women with overactive bladder 101 (46%) had neither painful bladder filling nor urinary urgency, 94 (43%) had either symptom and 23 (11%) had both symptoms. When controlling for age, women with either or both urological pain symptoms were more likely to have irritable bowel syndrome, chronic pelvic pain and temporomandibular disorder than women in the neither group. Additionally, these women had higher pain intensity and somatic symptoms scores than women with neither symptom.

conclusionsThe majority of women with overactive bladder who had not been diagnosed with interstitial cystitis/bladder pain syndrome reported painful urgency and/or painful filling. Experiencing painful urgency and/or filling was associated with an increased somatic symptom burden and greater pain intensity. These findings support the hypothesis that overactive bladder and interstitial cystitis/bladder pain syndrome diagnoses may represent a continuum of bladder hypersensitivity.

Indexed as

AdultChronic PainFemaleHumansMiddle AgedPain MeasurementPelvic PainPrognosisSeverity of Illness IndexSurveys and QuestionnairesUrinary Bladder, Overactivechronic paincystitisinterstitialnociceptive painoveractivepatient reported outcome measuresurinary bladder

Identifiers

PMID30017963
PMCPMC6298830
OpenAlexW2816597823

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.