Evidence map›Paper›PMID 30017700›Full record

ArticleJournal of structural biology2018

Evaluation system and web infrastructure for the second cryo-EM model challenge.

Andriy Kryshtafovych, Paul D Adams, Catherine L Lawson, Wah Chiu

Abstract read
In one paragraph

Article in Journal of structural biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Evolving data standards for cryo-EM structures.Structural dynamics (Melville, N.Y.) · 2020
    Article
  5. Article
  6. Comparing cryo-EM structures.Journal of structural biology · 2018
    Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andriy KryshtafovychGenome Center, University of California, Davis, 451 Health Sciences Drive, Davis, CA 95616, USA. Electronic address: akryshtafovych@ucdavis.edu.
Paul D AdamsMolecular Biophysics & Integrated Bioimaging, LBNL, CA 94720, USA; Department of Bioengineering, University of California Berkeley, CA 94720, USA.
Catherine L LawsonInstitute for Quantitative Biomedicine and Research Collaboratory for Structural Bioinformatics, Rutgers, The State University of New Jersey, 174 Frelinghuysen Road, Piscataway, NJ 08854, USA.
Wah ChiuDepartments of Bioengineering and Microbiology & Immunology, Stanford University, Stanford, CA 94305-5447, USA; Division of CryoEM and Bioimaging, SLAC National Accelerator Laboratory, Menlo Park, CA 94025, USA.

Funding

PROJECT 5 - DUKE - STRUCTURE VALIDATION AND IMPROVEMENT FOR PROTEINS AND N. ACIDSP01GM063210 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI ADAMS, PAUL DAVID · 2001 to 2021
$33.5M
Unified Data Resource for Large Complexes Determined by Cryo-Electron MicroscopyR01GM079429 · NIGMS · STANFORD UNIVERSITY · PI CHIU, WAH · 2007 to 2021
$11.6M
NIGMS NIH HHS P01 GM063210NIGMS NIH HHS R01 GM079429
6 · The paper itself

Abstract

An evaluation system and a web infrastructure were developed for the second cryo-EM model challenge. The evaluation system includes tools to validate stereo-chemical plausibility of submitted models, check their fit to the corresponding density maps, estimate their overall and per-residue accuracy, and assess their similarity to reference cryo-EM or X-ray structures as well as other models submitted in this challenge. The web infrastructure provides a convenient interface for analyzing models at different levels of detail. It includes interactively sortable tables of evaluation scores for different subsets of models and different sublevels of structure organization, and a suite of visualization tools facilitating model analysis. The results are publicly accessible at http://model-compare.emdatabank.org.

Indexed as

Cryoelectron MicroscopyModels, MolecularProtein ConformationProteinsProteinsCryo-EMModel challengeProtein structure modelingProtein structure verification

Identifiers

PMID30017700
PMCPMC6205695

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.