Evidence map›Paper›PMID 30017492›Full record

SynthesisSleep medicine reviews2018

The impact of alcohol on breathing parameters during sleep: A systematic review and meta-analysis.

Bhanu Prakash Kolla, Moein Foroughi, Farzane Saeidifard, Subhajit Chakravorty, Zhen Wang, Meghna P Mansukhani

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Sleep medicine reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 68 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. A Case of Mild OSA Exacerbated by Alcohol Use.Respirology case reports · 2025
    Article
  14. Article
  15. Article
  16. Impact of Developmental Alcohol Exposure on Sleep Physiology.Advances in experimental medicine and biology · 2025
    Review
  17. Article
  18. Article
  19. Recent advances in managing obstructive sleep apnea.World journal of clinical cases · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bhanu Prakash KollaCenter for Sleep Medicine, Mayo Clinic, Rochester, MN, USA; Department of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, USA. Electronic address: kolla.bhanuprakash@mayo.edu.
Moein ForoughiDepartment of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, USA.
Farzane SaeidifardDivision of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.
Subhajit ChakravortyDepartment of Psychiatry, Perelman School of Medicine, Philadelphia, PA, USA.
Zhen WangCenter for Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA.
Meghna P MansukhaniCenter for Sleep Medicine, Mayo Clinic, Rochester, MN, USA.
Mayo Clinic · USMayo Clinic in Arizona · US

Funding

CSRD VA IK2 CX000855
6 · The paper itself

Abstract

Alcohol, a muscle relaxant, can potentially worsen obstructive sleep apnea (OSA) but the literature on the effects of alcohol on OSA is conflicting. This systematic review and meta-analysis of randomized controlled trials examined the impact of alcohol on breathing parameters during sleep. Ovid Medline, Embase and PsycINFO databases were queried through November 1, 2017 for studies that reported objective measures of breathing during sleep, prior to and after alcohol administration. Weighted mean differences (WMD) and 95% confidence intervals (CI) were calculated for apnea-hypopnea index (AHI) and mean oxyhemoglobin saturation (SpO2). Secondary outcome measures were examined where available. The meta-analysis of 14 eligible studies (n = 422; 71.9% male) found that AHI increased significantly after alcohol administration (WMD = 2.33; 95% CI = 1.41 to 3.25, I

Indexed as

Randomized Controlled Trials as TopicAlcohol DrinkingHumansOxygenSleep Apnea, ObstructiveOxygenAlcoholOxygen saturationSleep apnea

Identifiers

PMID30017492
PMCPMC8520474
OpenAlexW2808647129

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.